Actively Recruiting

Phase Not Applicable
Age: 12Years - 65Years
All Genders
NCT06769464

Electrophysiological Representations of Odor in the Human Brain Study 1

Led by Northwestern University · Updated on 2025-01-13

28

Participants Needed

1

Research Sites

226 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Investigating representations of odor intensity in human piriform cortex. To identify a neural representation of perceived odor intensity, it is necessary to dissociate stimulus concentration from perceived intensity. Experiments for this aim will measure human perceptual responses while manipulating intensity independently from concentration using two complementary approaches. In Experiment 1A, we will match perceived intensities across odors of different concentrations, allowing us to identify a neural representation of intensity that is independent of stimulus identity and concentration. In Experiment 1B, we will create conditions of different perceived intensity over constant odor stimuli using adaptation. Approaching the same question from different angles will strengthen the robustness of our findings. Preliminary data suggest that temporal features of the piriform neural response may represent odor intensity.

CONDITIONS

Official Title

Electrophysiological Representations of Odor in the Human Brain Study 1

Who Can Participate

Age: 12Years - 65Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Ages 12 to 65 years
  • English-speaking
  • Patients undergoing brain surgery for treatment of medically intractable epilepsy
Not Eligible

You will not qualify if you...

  • History of smell or taste problems

AI-Screening

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Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Northwestern University

Chicago, Illinois, United States, 60611

Actively Recruiting

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Research Team

N

Naelly Arriaga, MPH

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

BASIC_SCIENCE

Number of Arms

1

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Electrophysiological Representations of Odor in the Human Brain Study 1 | DecenTrialz