Actively Recruiting
Electrophysiological Representations of Odor in the Human Brain Study 1
Led by Northwestern University · Updated on 2025-01-13
28
Participants Needed
1
Research Sites
226 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Investigating representations of odor intensity in human piriform cortex. To identify a neural representation of perceived odor intensity, it is necessary to dissociate stimulus concentration from perceived intensity. Experiments for this aim will measure human perceptual responses while manipulating intensity independently from concentration using two complementary approaches. In Experiment 1A, we will match perceived intensities across odors of different concentrations, allowing us to identify a neural representation of intensity that is independent of stimulus identity and concentration. In Experiment 1B, we will create conditions of different perceived intensity over constant odor stimuli using adaptation. Approaching the same question from different angles will strengthen the robustness of our findings. Preliminary data suggest that temporal features of the piriform neural response may represent odor intensity.
CONDITIONS
Official Title
Electrophysiological Representations of Odor in the Human Brain Study 1
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Ages 12 to 65 years
- English-speaking
- Patients undergoing brain surgery for treatment of medically intractable epilepsy
You will not qualify if you...
- History of smell or taste problems
AI-Screening
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Trial Site Locations
Total: 1 location
1
Northwestern University
Chicago, Illinois, United States, 60611
Actively Recruiting
Research Team
N
Naelly Arriaga, MPH
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
BASIC_SCIENCE
Number of Arms
1
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