Actively Recruiting
Electrophysiological Signature of Mild Cognitive Impairment and Its Relationship with Parkinson's Disease: a High-density EEG Investigation
Led by IRCCS San Camillo, Venezia, Italy · Updated on 2024-10-15
42
Participants Needed
1
Research Sites
97 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The study aims to investigate neural correlate of Mild Cognitive Impairment (MCI) in Parkinson's disease (PD) and to identify a link between functional impairment (in both cognitive and motor domains) and electrophysiological cortical sing of MCI in PD. A sample of 42 subjects will be divide into three subgroup: healthy control, PD with MCI (PD-MCI) and PD without MCI (PD-ctrl). Those subjects will undergo a specific neuropsychological evaluation and, to measure the electro-cortical activity, high-density electroencephalography (hdEEG) will be record during both resting state and cognitive tasks. Furthermore, hdEEG data will be combine with structural magnetic resonance to obtain information about network connectivity.
CONDITIONS
Official Title
Electrophysiological Signature of Mild Cognitive Impairment and Its Relationship with Parkinson's Disease: a High-density EEG Investigation
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Mini-Mental State Examination (MMSE) score greater than 24 or Montreal Cognitive Assessment (MoCA) score greater than 15.5
- If taking medications, must be on stable doses for at least 4 weeks before the study visit for anticholinesterase drugs, antidepressants, or Levodopa
- Signed informed consent form
You will not qualify if you...
- Severe dementia with MMSE score less than 24
- MoCA score less than 15.5
- On antipsychotic treatment for less than 3 months
- Uncontrolled other medical conditions
- Presence of metal prostheses, dentures, or any condition preventing MRI examination
- Inability to walk independently
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
IRCCS San Camillo S.R.L
Lido, Italy, Italy
Actively Recruiting
Research Team
F
Francesca Burgio, PhD
CONTACT
G
Giovanni Lazzaro, MSc
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
3
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