Actively Recruiting

Phase Not Applicable
Age: 21Years - 89Years
All Genders
NCT07348705

Electrophysiology-based DBS Programming for PD

Led by University of Florida · Updated on 2026-03-30

30

Participants Needed

1

Research Sites

260 weeks

Total Duration

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AI-Summary

What this Trial Is About

Deep brain stimulation (DBS) effectively alleviates motor symptoms in Parkinson's disease (PD). However, current programming is manual and time-consuming. This study will evaluate physiology-based programming using local field potentials (LFPs) to identify optimal stimulation parameters. Specifically, DBS contact selection based on beta power and a broad-band approach will be compared with conventional clinician-based programming.

CONDITIONS

Official Title

Electrophysiology-based DBS Programming for PD

Who Can Participate

Age: 21Years - 89Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Patients diagnosed with idiopathic Parkinson's disease according to Movement Disorder Society criteria
  • Have DBS implantation with the Percept DBS device (Medtronic, USA) for motor symptom treatment
  • Able to provide informed consent for the study
  • Willing to participate at the time of the initial programming session
  • Aged between 21 and 89 years old
Not Eligible

You will not qualify if you...

  • Cannot comply with the study protocol
  • Have atypical Parkinsonism
  • Have personality or mood symptoms that may interfere with study participation

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Norman Fixel Institute for Neurological Diseases

Gainesville, Florida, United States, 32608

Actively Recruiting

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Research Team

J

Joshua Wong, MD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

CROSSOVER

Primary Purpose

TREATMENT

Number of Arms

3

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