Actively Recruiting
EMDR Treatment in PTSD Following Cardiac Events
Led by University of Zurich · Updated on 2026-05-07
60
Participants Needed
1
Research Sites
366 weeks
Total Duration
On this page
Sponsors
U
University of Zurich
Lead Sponsor
E
EMDR Europe
Collaborating Sponsor
AI-Summary
What this Trial Is About
Cardiac events can often result in debilitating and persistent psychological symptoms. A key question involves whether optimal treatment of cardiac-induced posttraumatic stress disorder (PTSD) reduces PTSD symptoms and thereby may offset the risk of recurrent or worsening cardiovascular disease. Cardiac-induced PTSD 1) is prevalent, 2) features symptoms unique to internal ongoing somatic threat, with fears and worries that can be distinguished from PTSD resulting from external causes, 3) is persistent, 4) is associated with negative physical and emotional consequences, and 5) has not been the subject of randomized-controlled treatment trials (RCT). There is preliminary evidence suggesting that patients with cardiac-disease induced PTSD might particularly profit from EMDR. Nevertheless, this possibility has not been tested in cardiac-induced PTSD. Currently, patients with cardiac-induced PTSD are not routinely offered trauma-focused therapies, with a lack of scientific evidence likely being one major reason for this omission. If our proposed RCT shows that EMDR can be an effective treatment for patients with ACS-induced PTSD, EMDR could be routinely implemented as first-line treatment. The RCT outcomes might inform larger trials to test whether poor prognosis in terms of major adverse cardiovascular events can be improved through EMDR in patients with cardiac-induced PTSD.
CONDITIONS
Official Title
EMDR Treatment in PTSD Following Cardiac Events
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age between 18 and 70 years
- Male or female participants
- Diagnosis of STEMI (ST-elevation myocardial infarction) or non-STEMI (troponin positive) confirmed by a cardiologist at the time of the cardiac event
- Diagnosis of PTSD caused by the cardiac event
You will not qualify if you...
- Diagnosis of psychotic disorder, bipolar disorder, or substance abuse as measured by the Mini International Neuropsychiatric Interview (M.I.N.I)
- Acute suicidal thoughts as assessed by the M.I.N.I
- Use of non-selective beta blockers (e.g., propranolol) during the study period
- Ongoing psychological or psychiatric treatment outside of this trial during the study period
- Vision problems such as strabismus that prevent adequate eye movement
- Insufficient knowledge of the German language
- Expected inability or unwillingness to follow the study protocol
- Regular use of benzodiazepine medication
AI-Screening
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Trial Site Locations
Total: 1 location
1
University Hospital Zurich
Zurich, Switzerland
Actively Recruiting
Research Team
C
Christoph Mueller-Pfeiffer, PD Dr. med.
CONTACT
M
Mary Princip, PD Dr. phil.
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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