Actively Recruiting
EMG-guided Botox Injection Versus Conventional Botox Injection in Gummy Smile Patients
Led by Cairo University · Updated on 2026-03-20
32
Participants Needed
1
Research Sites
91 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The goal of this clinical trial is to compare the effect of EMG-guided Botox injection with conventional Botox injection in Yonsei point, in patients with excessive gingival display. The main question it aims to answer is: • Does the use of electromyography (EMG) as a guide during Botox injection for patients with gummy smile has better effect than conventional injection in Yonsei point? Participants will be randomized in equal proportions between intervention and control groups. * Preoperative assessment of amount of gingival display, lip length (philtrum and vermilion length), and smile type. * For the intervention group, EMG readings will be done in Clinical Neurophysiology Department, Kasr Al-Ainy Hospital EMG-guided Botox injection (Intervention group). Conventional Botox injection in Yonsei point (Control group).
CONDITIONS
Official Title
EMG-guided Botox Injection Versus Conventional Botox Injection in Gummy Smile Patients
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients with excessive gingival display
- Patients with esthetic concerns
- Patients with mild to moderate vertical maxillary excess (VME)
- Normal clinical crown dimensions
- Patients aged 18 to 50
- Systemically healthy patients
- Non-smokers
You will not qualify if you...
- Patients with severe vertical maxillary excess (VME)
- Pregnant and breastfeeding women
- Patients with gingival inflammation and/or enlargement
- Inflammation or infection at the site of injection
- Patients allergic to any Botox components (saline, human albumin, lactose, sodium succinate)
- Patients using anticholinesterase or agents affecting neuromuscular transmission
- Psychologically unstable patients or those with unrealistic expectations
- Patients with neuromuscular disorders (e.g., myasthenia gravis, Eaton-Lambert syndrome)
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
Faculty of Dentistry, Cairo University
Cairo, Egypt
Actively Recruiting
Research Team
S
Sherry Fayez Akhnokh, BSc
CONTACT
N
Nesma Shemais, PhD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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