Actively Recruiting
Emotion Regulation-based Internet-delivered Cognitive Behavioural Therapy for Premenstrual Dysphoric Disorder
Led by Uppsala University · Updated on 2025-07-31
164
Participants Needed
1
Research Sites
154 weeks
Total Duration
On this page
Sponsors
U
Uppsala University
Lead Sponsor
F
Friedrich-Alexander-Universität Erlangen-Nürnberg
Collaborating Sponsor
AI-Summary
What this Trial Is About
Premenstrual dysphoric disorder (PMDD) is a debilitating cyclic mental disorder affecting about 2-5% of women of reproductive age. PMDD is characterised by recurring emotional, behavioural, cognitive, and somatic symptoms that arise during the luteal (premenstrual) phase of the menstrual cycle and remit shortly after the onset of menses. Although pharmacological interventions are available, many women experience residual symptoms, discontinue treatment or refrain from them because of side effects. Therefore, non-pharmacological treatment options are needed. Preliminary evidence suggests that internet-delivered cognitive behavioural therapy (ICBT) is a promising candidate, but further research is warranted. Also, there is room for treatment improvement. Specifically, it has been suggested that components targeting emotional and interpersonal dysregulation should be incorporated into CBT for PMDD. The current study aims to assess the effects of an ICBT intervention for PMDD incorporating skills training in emotion regulation and interpersonal effectiveness in a randomised controlled trial (RCT).
CONDITIONS
Official Title
Emotion Regulation-based Internet-delivered Cognitive Behavioural Therapy for Premenstrual Dysphoric Disorder
Who Can Participate
Eligibility Criteria
You may qualify if you...
- PMDD diagnosis according to DSM-5
- Menstrual cycle length between 23-34 days (5-8 cycles in the last six months)
- Sufficient proficiency in Swedish to understand treatment materials
- Access to a computer, tablet, or mobile phone with internet connection
You will not qualify if you...
- Breastfeeding or pregnancy during the past three months
- Starting or changing antidepressants, benzodiazepines, contraceptives, or hormones in the last three months
- Current or past gynecological diseases like endometriosis or polycystic ovary syndrome that may affect results
- Ongoing or previous psychological treatment for premenstrual disorders
- Severe mental disorders such as psychosis, bipolar disorder, severe eating disorder, or severe depression that could interfere with treatment
- Elevated suicide risk including active suicidal thoughts, plans, or previous attempts
AI-Screening
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Trial Site Locations
Total: 1 location
1
Uppsala university
Uppsala, Uppsala County, Sweden, 75656
Actively Recruiting
Research Team
J
Johanna Motilla Hoppe, PhD
CONTACT
M
Monica Buhrman, Associate Professor
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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