Actively Recruiting
Emotion and Symptom-Focused Engagement Trial for Individuals With Acute Leukemia
Led by Canadian Cancer Trials Group · Updated on 2026-03-27
266
Participants Needed
5
Research Sites
285 weeks
Total Duration
On this page
Sponsors
C
Canadian Cancer Trials Group
Lead Sponsor
C
Canadian Cancer Society (CCS)
Collaborating Sponsor
AI-Summary
What this Trial Is About
The purpose of this study is to find out whether a novel manualized intervention, called Emotion and Symptom-focused Engagement (EASE), that combines psychological support with symptom screening plus triggered referral to early palliative care for symptom control, reduces psychological distress and physical symptom burden in individuals newly diagnosed with acute leukemia. To do this, half of the participants in this study will receive the usual care offered to patients with acute leukemia and half of the participants will receive usual care plus the EASE intervention.
CONDITIONS
Official Title
Emotion and Symptom-Focused Engagement Trial for Individuals With Acute Leukemia
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Newly diagnosed acute leukemia (AML, ALL, CML in blast crisis, T-cell leukemia lymphoma, or ambiguous lineage) recruited up to 1 week before or within 2 weeks of hospital admission
- Receiving or expected to receive induction therapy with curative intent at recruitment
- Age 18 years or older
- Ability to pass cognitive screening test (SOMC score 6 20) or deemed suitable by CRA
- Fluent in English and willing and able to complete baseline questionnaires in English
You will not qualify if you...
- Major communication difficulties at recruitment (e.g., severe hearing impairment or inability to speak)
- Currently receiving in-hospital psychological or psychiatric counseling
- Currently receiving in-hospital palliative care services
- Diagnosis of acute promyelocytic leukemia
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 5 locations
1
Juravinski Cancer Centre at Hamilton Health Sciences
Hamilton, Ontario, Canada, L8V 5C2
Actively Recruiting
2
Kingston Health Sciences Centre
Kingston, Ontario, Canada, K7L 2V7
Actively Recruiting
3
Ottawa Hospital Research Institute
Ottawa, Ontario, Canada, K1H 8L6
Actively Recruiting
4
Odette Cancer Centre
Toronto, Ontario, Canada, M4N 3M5
Actively Recruiting
5
University Health Network
Toronto, Ontario, Canada, M5G 2M9
Actively Recruiting
Research Team
H
Harriet Richardson
CONTACT
L
Lois Shepherd
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
SUPPORTIVE_CARE
Number of Arms
2
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here