Actively Recruiting
Emotional and Neutral Sounds for Neurophysiological Prognostic Assessment of Critically Ill Patients With a Disorder of Consciousness
Led by Assistance Publique - Hôpitaux de Paris · Updated on 2025-09-12
114
Participants Needed
2
Research Sites
127 weeks
Total Duration
On this page
Sponsors
A
Assistance Publique - Hôpitaux de Paris
Lead Sponsor
U
URC-CIC Paris Descartes Necker Cochin
Collaborating Sponsor
AI-Summary
What this Trial Is About
The purpose of this study is to determine if the use of emotional sound as subject own name (SON) pronounced by a familiar voice (FV) compared to SON pronounced by a non-familiar voice (NFV) during event related potential (ERP) produced a more reliable neurophysiological P300 responses, and to assess the prognostic value of this P300 responses induced by the SON with a FV.
CONDITIONS
Official Title
Emotional and Neutral Sounds for Neurophysiological Prognostic Assessment of Critically Ill Patients With a Disorder of Consciousness
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients hospitalized in ICU for cardiac arrest, stroke, subarachnoid haemorrhage, or head trauma
- Persistent disorder of consciousness 12 hours after sedation weaning
- Patients previously assessed with event related potentials using only neutral sounds between April 2022 and December 2022
You will not qualify if you...
- Moribund patient
- Uncontrolled shock during neurophysiological evaluation
- Sedated patient
- Minor patient
- Brain death
- Known deafness
- Pregnant woman
- Prior inclusion in the study
- Patient not affiliated to a social security system
- Implementation of limitations and stop of active therapies
- Patient under legal protection
- Patient benefiting from State Medical Aid
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 2 locations
1
Medical ICU, HEGP Hospital, APHP.Centre
Paris, IDF, France, 75015
Not Yet Recruiting
2
Medical ICU, Cochin Hospital, APHP.Centre
Paris, Île-de-France Region, France, 75014
Actively Recruiting
Research Team
S
Sarah Benghanem, MD, MSc, PhD student
CONTACT
M
Marie BENHAMMANI-GODARD
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
2
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here