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ID06120426

Comparing En Bloc Surgery and Separation Surgery with Radiotherapy for Treating Spinal Oligometastatic Tumors A Multi-center Prospective Study on Patient Survival and Outcomes

Led by Shanghai Changzheng Hospital · Updated on 2023-11-13

182

Participants Needed

1

Research Sites

104 weeks

Total Duration

AI-Summary

What this Trial Is About

This research aims to explore how two types of surgeries combined with radiation therapy affect prognosis and survival in patients with spinal oligometastatic cancer. Patients with fewer metastatic sites often have better outcomes, and aggressive local treatments like surgery and targeted radiotherapy may improve survival. The study seeks to clarify the impact of these treatments on clinical outcomes and guide future care for spinal oligometastatic tumors. The trial compares two approaches total en bloc spondylectomy, a complex surgery that removes the tumor and aims to relieve spinal compression and delay recurrence, and separation surgery followed by radiotherapy after recovery. Both treatments are for patients diagnosed with spinal oligometastases. Researchers will observe clinical results to understand the benefits and optimize treatment goals. Participants will undergo surgical procedures and follow-up assessments including imaging scans, pain inventories, quality of life questionnaires, and monitoring for complications at multiple time points up to one year after surgery. The main outcome measured is overall survival from surgery until death related to the primary disease. Additional outcomes include local tumor control, progression-free survival, pain levels, quality of life, and complication rates. The study will help evaluate the effects of these treatments on patient prognosis and quality of care over time.

CONDITIONS

Brief Title

En Bloc Resection Versus Separation Surgery Combined With Radiotherapy for the Treatment of Spinal Oligometastatic Tumor.

Research Team

J

Jianru Xiao, Doctor

W

Wei Xu, Doctor

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