Actively Recruiting
End-on Versus Parallel Radiofrequency Lesioning for Neurotomy of the Cervical Medial Branch Nerves
Led by University Health Network, Toronto · Updated on 2026-01-16
72
Participants Needed
3
Research Sites
259 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Aim of the EndPaRL study is to compare the efficacy and effectiveness of the two techniques utilizing sharp straight conventional radiofrequency needle with a trident needle for radiofrequency neurotomy of Cervical Medial Branch Nerves (CMBNs), in patients presenting with chronic, moderate-to-severe, neck pain due to cervical zygapophyseal joint osteoarthritis, as diagnosed by positive responses to two consecutive diagnostic blocks with local anesthetic of the CMBN.
CONDITIONS
Official Title
End-on Versus Parallel Radiofrequency Lesioning for Neurotomy of the Cervical Medial Branch Nerves
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Adult patient of either gender aged 18-85 years
- Predominant axial (non-radicular) neck pain for at least 3 months
- Average neck pain score of 5 or higher on the Numerical Rating Scale over 7 days at baseline
- Moderate or greater functional impairment due to pain (Neck Disability Index score of 15 or higher out of 50)
- Failure to respond to conservative medical management, including pharmacologic and physical therapy, for at least 3 months
- Positive response to two consecutive diagnostic blocks of the cervical medial branch nerves with short and long-acting anesthetic
You will not qualify if you...
- Participants with financial incentives or litigation related to ongoing pain
- Inability to complete assessment instruments
- Presence of chronic widespread pain
- Prior radiofrequency neurotomy of the cervical medial branch nerves
- Severe mental health issues
- Pregnancy or other conditions preventing use of fluoroscopy
- Untreated bleeding disorders (coagulopathy)
- Systemic or local infection at the time of screening
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 3 locations
1
Women's College Hospital
Toronto, Ontario, Canada, M5S 1B3
Actively Recruiting
2
University Health Network (UHN)
Toronto, Ontario, Canada, M5T 2S8
Actively Recruiting
3
Division of Pain Medicine, Department of Anesthesiology, Reanimation, and Pain Medicine, Hospital Clínic de Barcelona, University of Barcelona.
Barcelona, Catalonia, Spain, 08036
Not Yet Recruiting
Research Team
D
Danielle Alvares, PhD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
DOUBLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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