Actively Recruiting
Endometrial Cancer Vaginal Fluid Specimen Collection Study
Led by Exact Sciences Corporation · Updated on 2026-04-22
4200
Participants Needed
1
Research Sites
110 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This is a multicenter, prospective, specimen collection study for development and evaluation of tests used to detect endometrial cancer, other cancers, or their causes.
CONDITIONS
Official Title
Endometrial Cancer Vaginal Fluid Specimen Collection Study
Who Can Participate
Eligibility Criteria
You may qualify if you...
- For Cohort 1: Age 45 years or older, or age 18 or older with at least one risk factor
- Diagnosed with abnormal uterine bleeding (AUB)
- Planning standard-of-care endometrial tissue sampling to assess for endometrial cancer or precancerous conditions
- For Cohort 2: Age 18 years or older
- Newly diagnosed, biopsy-confirmed endometrial cancer or precancerous conditions
- Planning initial management for their endometrial pathology
You will not qualify if you...
- Prior partial or complete hysterectomy
- Current pregnancy
- Prior pelvic or vaginal radiotherapy
- Chemotherapy within past 5 years (except tamoxifen)
- Any condition judged by the Investigator to preclude participation
- For Cohort 1: Cancer diagnosis within past 5 years (except non-gynecologic skin cancer)
- Current biopsy-proven cervical, vaginal, or vulvar cancer, or lower genital tract dysplasia
- Current biopsy-proven endometrial cancer, hyperplasia, or benign polyp
- Benign endometrial biopsy within last month
- For Cohort 2: Cancer diagnosis other than endometrial cancer within past 5 years (except non-gynecologic skin cancer)
- Prior cervical cancer or biopsy-proven cervical dysplasia
- Surgery for recurrent endometrial cancer
- Preoperative neoadjuvant chemotherapy or radiotherapy for current endometrial cancer
- Prior treatment or surgery to remove target pathology during current episode
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Murfreesboro Medical Clinic
Murfreesboro, Tennessee, United States, 37130
Actively Recruiting
Research Team
S
Sr. Clinical Trial Manager
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
2
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