Study of Ultrasound-Guided Ethanol Sclerotherapy for Treating Ovarian Endometrioma and Its Impact on Fertility and Ovarian Function

What this Trial Is About

This research investigates the use of ultrasonography US-guided ethanol sclerotherapy for treating ovarian endometriomas, which are cystic masses caused by endometrial tissue collecting fluid. These cysts can cause pelvic pain, painful menstruation, irregular uterine bleeding, and infertility. Endometriomas are commonly treated with medication or surgery, but this study explores a less invasive approach that may avoid damage to the ovary. The study involves women with endometriomas sized between 25 and 100 mm who will undergo US-guided aspiration of the cyst fluid followed by sclerotherapy using 95% ethanol. The ethanol is left inside the cyst for 10 to 15 minutes and then removed. This procedure is done under general anesthesia with antibiotic protection given beforehand. After the procedure, some participants may undergo in vitro fertilization IVF about a month later to assess fertility outcomes. Participants will be monitored to evaluate the effects of sclerotherapy on ovarian function and fertility treatment results over three years. Researchers will collect samples for cytology testing and track outcomes related to ovarian reserve and pregnancy rates. The study aims to measure how this treatment impacts ovarian health and IVF success while avoiding the ovarian damage sometimes caused by surgery.

Endometrioma Ethanol Sclerotherapy - Prospective Cohort Study Protocol