Actively Recruiting

Phase Not Applicable
Age: 18Years - 45Years
FEMALE
NCT06775769

Endometrioma Sclerotherapy and Ovarian Preservation

Led by Chelsea and Westminster NHS Foundation Trust · Updated on 2025-11-25

60

Participants Needed

1

Research Sites

149 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

A randomised controlled trial assessing ovarian reserve after laparoscopic ethanol sclerotherapy of ovarian endometrioma compared to standard treatment of surgical excision of endometrioma. Secondary outcomes will include endometrioma recurrence, symptomatology and inflammatory environment.

CONDITIONS

Official Title

Endometrioma Sclerotherapy and Ovarian Preservation

Who Can Participate

Age: 18Years - 45Years
FEMALE

Eligibility Criteria

Eligible

You may qualify if you...

  • Female (XX genotype, assigned female at birth)
  • Age 18-40
  • Suspected unilateral or bilateral ovarian endometrioma of 2 cm or larger on ultrasound or MRI
  • Suitable for laparoscopic excision of endometrioma due to cyst size, pain, or to assist assisted reproductive technology
Not Eligible

You will not qualify if you...

  • Postmenopausal status
  • Suspicion of malignancy
  • Unable to undergo transvaginal ultrasound
  • Declines participation
  • Unable to understand English information
  • Lacks capacity to consent at recruitment
  • Known safeguarding issues

AI-Screening

AI-Powered Screening

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Trial Site Locations

Total: 1 location

1

Chelsea and Westminster NHS Foundation Trust

London, United Kingdom, SW10 9NH

Actively Recruiting

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Research Team

S

Sarah Bennet, BSc MBBS MRCOG

CONTACT

T

Thomas Bainton, BM BCh MRCOG MA(Oxon)

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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