Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
NCT06339320

Endoscopic Sleeve Gastroplasty (ESG) for the Treatment of Obesity

Led by The Methodist Hospital Research Institute · Updated on 2024-04-01

150

Participants Needed

2

Research Sites

500 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The purpose of this study is to evaluate endoscopic sleeve gastroplasty (ESG) for the treatment of obesity. The ESG procedure is an U.S. Food and Drug Administration (FDA) approved procedure for the treatment of obesity - patients with a body mass index (BMI) 30-50 kg/m2. This procedure is FDA approved; however, Metabolic and Bariatric Surgery Accreditation and Quality Improvement Program (MBSAQIP)-Accredited centers (such as Houston Methodist Hospital) must receive approval from an Institutional Review Board (IRB) in order to perform primary procedures, such as ESG, that are not endorsed by the American Society for Metabolic and Bariatric Surgery (ASMBS).

CONDITIONS

Official Title

Endoscopic Sleeve Gastroplasty (ESG) for the Treatment of Obesity

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Patients with BMI 30 to 50 kg/m2
  • Patients unable to lose weight or maintain weight loss through diet and exercise
  • Lifestyle interventions may include diet and aerobic or anaerobic exercise, including resistance training
Not Eligible

You will not qualify if you...

  • Patients who are actively pregnant
  • Active tobacco use within 4 weeks prior to the procedure
  • Active gastric mucosal lesions
  • Active bleeding or potential bleeding gastric lesions such as ulcers, erosive gastritis, varices, or vascular malformations
  • Neoplastic lesions including esophageal, gastric, or small bowel cancer
  • Hiatal hernia larger than 5 cm
  • Severe coagulopathy or antiplatelet/anticoagulant therapy that cannot be corrected
  • Psychiatric disorders not cleared by a psychologist or psychiatrist involved in the patient's care, including untreated affective disorders and all eating disorders
  • Patients with contraindications to endoscopic interventions

AI-Screening

AI-Powered Screening

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Trial Site Locations

Total: 2 locations

1

Houston Methodist Hospital

Houston, Texas, United States, 77030

Actively Recruiting

2

Houston Methodist Hospital - Sugarland

Sugar Land, Texas, United States, 77479

Actively Recruiting

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Research Team

T

Thomas R McCarty, MD, MPH

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

TREATMENT

Number of Arms

1

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