Study of Endoscopic Submucosal Dissection for Treating Early Gastrointestinal Neoplasia in Adults in the UK

What this Trial Is About

This study evaluates the use of endoscopic submucosal dissection ESD as a treatment for early gastrointestinal neoplasia. It is a multicenter cohort study conducted in the United Kingdom to assess the effectiveness and safety of ESD for removing early dysplastic or neoplastic lesions in the gastrointestinal tract. The research aims to provide detailed information on patient demographics and lesion characteristics, such as size and location. Participants undergo the ESD procedure, which uses an endoscopic knife to remove lesions in one piece en bloc from the gastrointestinal tract. Data will be collected on key outcomes including en bloc resection rates, curative resection rates, R0 resection rates, and complications or adverse events. The study includes a follow-up period of two years during which these outcomes and any mortality are monitored. Throughout the study, patient information and clinical details are gathered to evaluate the procedures success and safety. Follow-up assessments occur over two years to capture outcomes such as curative resection rates and any complications within 28 days post-procedure. Researchers will also monitor mortality rates over the two-year period. The total participation duration is approximately two years, with data collected at specified timepoints to understand the procedures impact.

Endoscopic Submucosal Dissection for Early GI Neoplasia in the United Kingdom