Prospective Evaluation of Endoscopic Submucosal Dissection (ESD) for Gastrointestinal Lesions in Western Patients

What this Trial Is About

Researchers are evaluating the use of Endoscopic Submucosal Dissection (ESD) to treat gastrointestinal lesions in a Western population. This observational study aims to record procedural and clinical outcomes of ESD performed during routine medical care, without experimental interventions. The study addresses differences in patient populations and lesion locations compared to Asian countries where ESD is more common, especially for early gastric cancer. ESD is a newer outpatient procedure that removes deep tumors from the gastrointestinal tract in one piece, allowing detailed analysis of the lesion and reducing recurrence compared to Endoscopic Mucosal Resection (EMR). This registry collects prospective data on patients undergoing ESD, who will continue to receive standard medical care throughout the study. Participants will be monitored for up to 12 months to evaluate the effectiveness of ESD for gastrointestinal lesion treatment. Researchers will review outcomes such as en-bloc resection rate, complete and curative resection rates, and safety including adverse events. No experimental treatments are given, and the study focuses on real-world clinical outcomes with standard care.

Endoscopic Submucosal Dissection (ESD)