Actively Recruiting

Age: 18Years +
All Genders
Healthy Volunteers
ID04403074

Endoscopic Ultrasound-Guided Celiac Plexus Neurolysis (EUS-CPN) for Chronic Pancreatitis, Database Repository

Led by Indiana University · Updated on 2026-02-18

35

Participants Needed

1

Research Sites

N/A

Total Duration

On this page

AI-Summary

What this Trial Is About

Chronic pancreatitis causes severe abdominal pain that is difficult to manage. This research is focused on collecting data about the use of endoscopic ultrasound-guided celiac plexus neurolysis (EUS-CPN) to control pain in people with chronic pancreatitis. The study aims to understand the clinical impact of this procedure and help physicians improve patient care. Participants who have chronic pancreatitis and receive minimal pain relief from celiac plexus blocks (lasting less than one month) may undergo celiac plexus neurolysis. This procedure involves injecting alcohol near the celiac plexus nerves under ultrasound guidance to reduce pain signals. The study collects data from these procedures performed by specialized physicians. During the study, participants' pain intensity and pain medication use are monitored immediately after the procedure and weekly for 24 weeks through phone follow-ups. Researchers track numeric pain scores and medication dosage to evaluate pain management. The study helps doctors better understand pain control in chronic pancreatitis and may improve treatment approaches over time.

CONDITIONS

Brief Title

Endoscopic Ultrasound-Guided Celiac Plexus Neurolysis (EUS-CPN) for Chronic Pancreatitis

Who Can Participate

Age: 18Years +
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • 18 years of age or older
  • Referral for the treatment of pain related to chronic pancreatitis
Not Eligible

You will not qualify if you...

  • Less than 18 years of age
  • Absence of chronic pancreatitis

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

1
2
3
+1

Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 visit (in-person)

Implementation

Duration - 1 day

Participants undergo the endoscopic ultrasound-guided celiac plexus neurolysis procedure to manage pain associated with chronic pancreatitis.

1 procedure visit (in-person)

Long-term Monitoring

Duration - Up to 24 weeks

Participants are monitored through weekly phone call follow-ups to assess pain intensity and pain medication usage after the procedure.

Weekly phone call follow-ups for up to 24 weeks

Trial Site Locations

Total: 1 location

1

Indiana University Hospital

Indianapolis, Indiana, United States, 46202

Actively Recruiting

Loading map...

Research Team

M

Mohammad Al-Haddad

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

1

Similar Trials

A Pilot Clinical Trial of Paricalcitol for Chronic Pancreati...

Chronic Pancreatitis

Actively Recruiting

1 location

Open-Label Study of Human Secretin Injection on Pancreatic F...

Exocrine Pancreatic Insufficiency

Actively Recruiting

1 location

A Multicenter Clinical Study on AI-Powered Precision Decisio...

Pancreatic Cancer

Actively Recruiting

1 location

Frequently Asked Questions

Have more questions? Get in touch with our team for quick support

Not the Right Trial for You?

Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.

Already have an account? Log in here