Actively Recruiting
Endothelial Dysfunction for Prognosis In Patients With preeClampSia
Led by Heidelberg University · Updated on 2025-05-11
385
Participants Needed
1
Research Sites
112 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Preeclampsia is a pregnancy-specific hypertensive disorder and can progress rapidly to severe adverse outcomes affecting both the mother and the fetus. Endothelial and microcirculatory dysfunction mediate systemic preeclampsia-related organ dysfunctions. Changes in endothelial and vascular function in preeclampsia have been demonstrated through reduced flow-mediated vasodilation as a result of reduced availability of nitric oxide, which potentially persists up to several years postpartum. Hyperspectral imaging is a new innovative technology that allows to assess the peripheral microcirculation and perfusion non-invasively and contactless, but has never been evaluated in the context of preeclampsia before. This EPICS project (Endothelial dysfunction for Prognosis In patients with preeClampSia) is a prospective observational study and aims to investigate hyperspectral imaging as a new potential diagnostic and prognostic marker in preeclampsia.
CONDITIONS
Official Title
Endothelial Dysfunction for Prognosis In Patients With preeClampSia
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Singleton pregnancies
- Age 18 years or older
- Ability to provide consent
- Written informed consent
You will not qualify if you...
- Lack of consent
- Language barrier
- Dark to very dark skin type
- Severe fetal chromosomal, genetic, or structural anomalies
- Laboratory changes in LDH, creatinine, or platelets due to other causes (e.g., isolated thrombocytopenia, immune thrombocytopenia, carcinoma)
AI-Screening
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Trial Site Locations
Total: 1 location
1
Heidelberg University Hospital, Department of Gynecology and Obstetrics
Heidelberg, Germany, 69120
Actively Recruiting
Research Team
D
Dr. med. Anna Scholz
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
4
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