Actively Recruiting

Age: 18Years +
All Genders
NCT05609123

Endothelial Glycocalyx Damage in Brain Death Organ Donors

Led by University Hospital Hradec Kralove · Updated on 2026-05-01

100

Participants Needed

1

Research Sites

312 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The study aims the assessment of endothelial glycocalyx (EG) degradation in deceased organ donors. There is a lack of organs for the transplantation program. By the description of the EG status, we can open room for organ optimization before transplantation and improve the organ function after transplantation in marginal donors.

CONDITIONS

Official Title

Endothelial Glycocalyx Damage in Brain Death Organ Donors

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Patients in critical condition declared as brain dead by clinical examination
Not Eligible

You will not qualify if you...

History of severe allergic reactions to study medication Currently pregnant or breastfeeding Recent participation in another clinical trial within the last 30 days Presence of uncontrolled medical conditions that could affect safety

AI-Screening

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Trial Site Locations

Total: 1 location

1

University Hospital Hradec Kralove

Hradec Králové, Czechia, 50005

Actively Recruiting

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Research Team

D

David Astapenko, MD, PhD

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

1

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