Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
NCT07130123

Endotracheal Suctionning During Positive Pressure Extubation in ICU

Led by Centre Hospitalier Régional d'Orléans · Updated on 2025-12-19

120

Participants Needed

1

Research Sites

104 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The aim of this clinical trial is to evaluate endotracheal suctioning during positive pressure extubation in mechanically ventilated adult patients (over 18 years old) in the intensive care unit (ICU). The main question it aims to answer is whether the intervention improves the respiratory oxygenation index (ROX) three hours after extubation compared to no endotracheal suction during positive pressure extubation. Participants will only need to be extubated by the nursing team in the ICU. Follow-up will consist of evaluating respiratory rate, pulse oximetry and inspired oxygen fraction for three hours following extubation.

CONDITIONS

Official Title

Endotracheal Suctionning During Positive Pressure Extubation in ICU

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Adult patient
  • Intubated for more than 48 hours
  • Patient for whom extubation is prescribed by the patient's physician
Not Eligible

You will not qualify if you...

  • Headboard restriction greater than 30°
  • Decision to limit active treatment in advance of reintubation
  • Protected person (under guardianship or curatorship)
  • Person under court protection
  • Persons deprived of liberty
  • Persons not affiliated to a social security scheme
  • Pregnant or breast-feeding woman
  • No co-inclusion with a study whose period of interest is follow-up within 3 hours of extubation

AI-Screening

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Trial Site Locations

Total: 1 location

1

Centre Hospitalier Universitaire d'Orléans

Orléans, Loiret, France, 45067

Actively Recruiting

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Research Team

C

Cécile FOSSAT

CONTACT

F

Fanny LOUAT

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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