Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
NCT07287293

Endotracheal Tube Suctioning Versus No Suctioning During Emergence From General Anesthesia

Led by Mahidol University · Updated on 2026-01-12

408

Participants Needed

1

Research Sites

64 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The goal of this study is to determine whether omitting tracheal suctioning immediately prior to extubation is non-inferior to routine tracheal suctioning with respect to early postoperative oxygenation among adult surgical patients (aged 18-90 years, American Society of Anesthesiologists \[ASA\] physical status I-III) undergoing elective surgery under general anesthesia with endotracheal intubation. The study addresses the following questions: * Primary outcome (non-inferiority): * Is the risk of postoperative desaturation (oxygen saturation \[SpO₂\] \<92% within 60 minutes after extubation) in the no-suction group not worse than in the routine-suction group by more than 10 percentage points? * Secondary outcomes (superiority): * Does omitting tracheal suctioning reduce postoperative cough severity and sore throat? * Does omitting tracheal suctioning avoid increasing extubation-related adverse events? Participants will be randomly assigned (1:1) to one of two groups: * Routine suctioning (SUC): Endotracheal suctioning plus oropharyngeal suctioning immediately before extubation * No suctioning (NON-SUC): Oropharyngeal suctioning only, without endotracheal suctioning All participants will receive standard anesthetic care and postoperative monitoring in the post-anesthesia care unit (PACU) for 60 minutes. Follow-up for airway symptoms and patient satisfaction will be conducted at 24 hours after surgery.

CONDITIONS

Official Title

Endotracheal Tube Suctioning Versus No Suctioning During Emergence From General Anesthesia

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Adults aged 18-90 years with American Society of Anesthesiologists (ASA) physical status I-III
  • Scheduled for elective surgery under general anesthesia requiring endotracheal intubation
  • Planned tracheal extubation in the operating room at the end of surgery
Not Eligible

You will not qualify if you...

  • Unable to provide informed consent or significant language barrier
  • Known obstructive sleep apnea, active pneumonia, or chronic pulmonary disease
  • Body mass index (BMI) greater than 35 kg/m²
  • Pregnant or increased risk of aspiration (e.g., full stomach)
  • Scheduled for maxillofacial, head and neck, or airway surgery
  • Anticipated surgery lasting more than 3.5 hours
  • Anticipated difficult airway with two or more predictors of difficult mask ventilation or history of difficult intubation

AI-Screening

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Trial Site Locations

Total: 1 location

1

Somdetphraphutthaloetla hospital

Samut Sakhon, Thailand, 75000

Actively Recruiting

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Research Team

S

Saowaluk Sotananan, Doctor of Medicine

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

SUPPORTIVE_CARE

Number of Arms

2

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