Actively Recruiting
Endotracheal Tube Suctioning Versus No Suctioning During Emergence From General Anesthesia
Led by Mahidol University · Updated on 2026-01-12
408
Participants Needed
1
Research Sites
64 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The goal of this study is to determine whether omitting tracheal suctioning immediately prior to extubation is non-inferior to routine tracheal suctioning with respect to early postoperative oxygenation among adult surgical patients (aged 18-90 years, American Society of Anesthesiologists \[ASA\] physical status I-III) undergoing elective surgery under general anesthesia with endotracheal intubation. The study addresses the following questions: * Primary outcome (non-inferiority): * Is the risk of postoperative desaturation (oxygen saturation \[SpO₂\] \<92% within 60 minutes after extubation) in the no-suction group not worse than in the routine-suction group by more than 10 percentage points? * Secondary outcomes (superiority): * Does omitting tracheal suctioning reduce postoperative cough severity and sore throat? * Does omitting tracheal suctioning avoid increasing extubation-related adverse events? Participants will be randomly assigned (1:1) to one of two groups: * Routine suctioning (SUC): Endotracheal suctioning plus oropharyngeal suctioning immediately before extubation * No suctioning (NON-SUC): Oropharyngeal suctioning only, without endotracheal suctioning All participants will receive standard anesthetic care and postoperative monitoring in the post-anesthesia care unit (PACU) for 60 minutes. Follow-up for airway symptoms and patient satisfaction will be conducted at 24 hours after surgery.
CONDITIONS
Official Title
Endotracheal Tube Suctioning Versus No Suctioning During Emergence From General Anesthesia
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Adults aged 18-90 years with American Society of Anesthesiologists (ASA) physical status I-III
- Scheduled for elective surgery under general anesthesia requiring endotracheal intubation
- Planned tracheal extubation in the operating room at the end of surgery
You will not qualify if you...
- Unable to provide informed consent or significant language barrier
- Known obstructive sleep apnea, active pneumonia, or chronic pulmonary disease
- Body mass index (BMI) greater than 35 kg/m²
- Pregnant or increased risk of aspiration (e.g., full stomach)
- Scheduled for maxillofacial, head and neck, or airway surgery
- Anticipated surgery lasting more than 3.5 hours
- Anticipated difficult airway with two or more predictors of difficult mask ventilation or history of difficult intubation
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
Somdetphraphutthaloetla hospital
Samut Sakhon, Thailand, 75000
Actively Recruiting
Research Team
S
Saowaluk Sotananan, Doctor of Medicine
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
SUPPORTIVE_CARE
Number of Arms
2
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