Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
ID07287293

Comparison of Endotracheal Tube Suctioning Versus No Suctioning During Emergence From General Anesthesia with Endotracheal Intubation: A Randomized, Single-Blind Study

Led by Mahidol University · Updated on 2026-01-12

408

Participants Needed

1

Research Sites

12 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Researchers are evaluating whether skipping tracheal suctioning right before removing a breathing tube is as safe as routine suctioning for adult patients aged 18 to 90 who undergo planned surgery under general anesthesia with endotracheal intubation. The study aims to see if avoiding suctioning affects early oxygen levels after the tube is removed and whether it impacts cough severity, sore throat, and other related side effects. Participants are randomly divided into two groups: one receiving routine suctioning inside the trachea and throat just before extubation, and the other receiving suctioning only in the throat without inserting the suction catheter into the trachea. All patients receive standard anesthesia care and are monitored in the post-anesthesia care unit (PACU) for 60 minutes after extubation. Airway symptoms and satisfaction are checked again 24 hours after surgery. During the study, participants will have their oxygen levels monitored closely for the first hour after extubation, along with assessments of coughing, sore throat severity, nausea, vomiting, and any extubation-related problems. Researchers will also record oxygen therapy needs and patient satisfaction at 24 hours. Safety monitoring continues up to 6 hours post-PACU arrival. Overall participation involves the surgery day and a follow-up at 24 hours post-surgery.

CONDITIONS

Brief Title

Endotracheal Tube Suctioning Versus No Suctioning During Emergence From General Anesthesia

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Adults aged 18 to 90 years with ASA physical status I-III
  • Scheduled for elective surgery under general anesthesia requiring endotracheal intubation
  • Planned tracheal extubation in the operating room at the end of surgery
Not Eligible

You will not qualify if you...

  • Inability to provide informed consent or significant language barrier
  • Known obstructive sleep apnea, active pneumonia, or chronic pulmonary disease
  • Body mass index over 35 kg/m²
  • Pregnancy or increased aspiration risk
  • Scheduled for maxillofacial, head and neck, or airway surgery
  • Anticipated surgery longer than 3.5 hours
  • Anticipated difficult airway with two or more predictors or history of difficult intubation

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 visit (in-person)

Treatment

Duration - During surgery and emergence from anesthesia

Participants receive either routine endotracheal suctioning or oropharyngeal suctioning only immediately prior to extubation during general anesthesia.

1 procedure visit (in-person)

Post-operative Follow-up

Duration - Up to 24 hours after surgery

Participants are monitored for postoperative desaturation, coughing, sore throat, oxygen therapy needs, nausea and vomiting, and extubation-related adverse events for up to 6 hours after arrival in the post-anesthesia care unit (PACU). Patient satisfaction is assessed approximately 24 hours after surgery.

1 follow-up visit in the first hour and 1 visit at 24 hours post-surgery

Trial Site Locations

Total: 1 location

1

Somdetphraphutthaloetla hospital

Samut Sakhon, Thailand, 75000

Actively Recruiting

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Research Team

S

Saowaluk Sotananan, Doctor of Medicine

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

SUPPORTIVE_CARE

Number of Arms

2

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Published Research Related To This Trial

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https://pubmed.ncbi.nlm.nih.gov/31587835

Test statistics and sample size formulae for comparative binomial trials with null hypothesis of non-zero risk difference or non-unity relative risk.

C P Farrington, G Manning

https://pubmed.ncbi.nlm.nih.gov/2281232

Pharmacological methods for reducing coughing on emergence from elective surgery after general anesthesia with endotracheal intubation: protocol for a systematic review of common medications and network meta-analysis.

Alan Tung, Nicholas A Fergusson, Nicole Ng...

https://pubmed.ncbi.nlm.nih.gov/30678727

Laryngotracheal topicalization with lidocaine before intubation decreases the incidence of coughing on emergence from general anesthesia.

Sean C Minogue, James Ralph, Martin J Lampa

https://pubmed.ncbi.nlm.nih.gov/15385385

Tracheal extubation with suction vs. positive pressure during emergence from general anaesthesia in adults: A randomised controlled trial.

Joël L'Hermite, Olivier Wira, Chritel Castelli...

https://pubmed.ncbi.nlm.nih.gov/28882741