Actively Recruiting
Endovascular Denervation for the Treatment of Patients With Peripheral Arterial Disease
Led by Zhongda Hospital · Updated on 2022-04-25
54
Participants Needed
1
Research Sites
218 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Sympathetic overactivity partly promotes the development of peripheral artery disease which mainly leads to ischemia of the lower limbs. Endovascular arterial denervation (ED) is a minimally invasive technique which could deliver Radiofrequency energy by a multi-electrode catheter to the Lower limb artery to restore Sympathetic activity. The purpose of this study is to evaluate the effects of multi-electrode radiofrequency ablation system on lower limb ischemia with PAD.
CONDITIONS
Official Title
Endovascular Denervation for the Treatment of Patients With Peripheral Arterial Disease
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Aged between 18 and 75 years
- Clinically confirmed peripheral arterial disease (PAD) patients classified in Rutherford categories II to VI
You will not qualify if you...
- Received thrombolytic therapy within the last 30 days
- Previous vascular bypass surgery
- Allergy or contraindication to antiplatelet drugs, anticoagulants, thrombolytic drugs, or contrast agents
- Bleeding disorders, coagulation dysfunction, hypercoagulability, or blood system diseases
- Serious liver or kidney diseases
- History of hemorrhagic stroke within the past month or ischemic stroke/transient ischemic attack within the past two weeks
- Having a pacemaker implant
- Pregnant, breastfeeding, or planning pregnancy
- Expected survival less than 24 months
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Zhongda Hospital, Southeast University
Nanjing, Jiangsu, China
Actively Recruiting
Research Team
G
Gao-Jun Teng, MD
CONTACT
G
Guo-Feng Zhao, MD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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