Actively Recruiting
Endovascular Treatment for Mild Ischemic Stroke Due to Acute Large Vessel Occlusion in the Anterior Circulation
Led by Wen-huo Chen · Updated on 2024-06-18
200
Participants Needed
9
Research Sites
417 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Explore the effectiveness and safety of emergency endovascular treatment in patients with mild ischemic stroke due to acute large vessel occlusion in the anterior circulation, identified through perfusion imaging.
CONDITIONS
Official Title
Endovascular Treatment for Mild Ischemic Stroke Due to Acute Large Vessel Occlusion in the Anterior Circulation
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age between 18 and 80 years old
- Stroke symptoms or last known well time within 24 hours before randomization
- Clinical diagnosis of acute ischemic stroke caused by large vessel occlusion in the anterior circulation confirmed by CTA or MRA
- Baseline NIHSS score less than 6 before randomization
- ASPECTS score of 6 or higher on non-contrast CT before randomization
You will not qualify if you...
- Premorbid Rankin Scale score of 2 or higher
- Known allergy to iodine, heparin, anesthesia, or other contraindications to endovascular treatment
- Severe or fatal co-morbidities such as malignant tumor, severe heart failure, or renal failure with life expectancy under 6 months
- Poorly controlled high blood pressure (systolic >220 mmHg or diastolic >120 mmHg)
- Blood glucose below 50 mg/dL or above 400 mg/dL
- Known bleeding disorders or recent anticoagulant treatments with abnormal blood clotting
- Seizures at stroke onset or during course affecting stroke severity assessment
- Pregnancy, lactation, or positive pregnancy test at admission
- Participation in another investigational drug or device study that may interfere
- Evidence of any intracranial hemorrhage on brain imaging
- Significant brain swelling or midline shift seen on imaging
- Conditions making endovascular treatment impossible, such as severe vessel abnormalities
- Aortic dissection
- Multiple large vessel occlusions making symptomatic vessel unclear
- Suspected or confirmed non-acute artery occlusion
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 9 locations
1
Zhangzhou Municipal Hospital
Zhangzhou, Fujian, China, 363000
Actively Recruiting
2
Gansu Provincial Hospital of Traditional Chinese Medicine
Lanzhou, Gansu, China, 730050
Actively Recruiting
3
Jiamusi Central Hospital
Jiamusi, Heilongjiang, China, 154000
Actively Recruiting
4
Ganzhou People's Hospital
Ganzhou, Jiangxi, China, 330000
Actively Recruiting
5
The First Affiliated Hospital of Nanchang University
Nanchang, Jiangxi, China, 330006
Actively Recruiting
6
Songyuan Jilin Oilfield Hospital
Songyuan, Jilin, China, 138000
Actively Recruiting
7
Shenyang First People's Hospital
Shenyang, Liaoling, China
Actively Recruiting
8
Lishui Central Hospital
Lishui, Zhejiang, China, 310000
Actively Recruiting
9
Taizhou First People's Hospital
Taizhou, Zhejiang, China, 310000
Actively Recruiting
Research Team
W
Wenhuo Chen, MD
CONTACT
T
Tingyu Yi, MD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
NON_RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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