Actively Recruiting
Engage Psychosocial Intervention for Cancer Symptoms
Led by Duke University · Updated on 2026-03-16
190
Participants Needed
1
Research Sites
177 weeks
Total Duration
On this page
Sponsors
D
Duke University
Lead Sponsor
N
National Cancer Institute (NCI)
Collaborating Sponsor
AI-Summary
What this Trial Is About
The goal of this clinical trial is to test the efficacy a new psychosocial symptom management intervention called ENGAGE for patients with Stage IV breast, prostate, lung, or colorectal cancer. Participants will be randomized to ENGAGE or a Supportive Care intervention. Patient-reported outcomes will be assessed at baseline, 2 months, and 4 months.
CONDITIONS
Official Title
Engage Psychosocial Intervention for Cancer Symptoms
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Receiving cancer care at a Duke Cancer Network clinic or the Duke Cancer Institute and living in a rural county at least 60 miles from Duke
- Oncologist confirmed Stage IV breast, prostate, lung, or colorectal cancer
- Worst pain, fatigue, or distress rated 3 or higher out of 10 in the past 7 days for at least 2 symptoms
- MD Anderson Symptom Inventory Interference with Daily Living Scale average score 3 or higher out of 10 in the past 7 days
- Eastern Cooperative Oncology Group performance status of 2 or lower
- At least 18 years old
- Ability to speak and read English
- Hearing and vision that allow completion of telehealth sessions
You will not qualify if you...
- Significant cognitive impairment shown in medical chart or during telephone mental status screening
- Serious psychiatric conditions such as schizophrenia or suicidal intent that prevent safe participation
- Participation in Cognitive-Behavioral Therapy or Acceptance and Commitment Therapy for cancer symptom management in the last 6 months
- Enrollment in hospice at screening
AI-Screening
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Trial Site Locations
Total: 1 location
1
Duke Cancer Network
Durham, North Carolina, United States, 27713
Actively Recruiting
Research Team
J
Joseph G Winger, PhD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
SUPPORTIVE_CARE
Number of Arms
2
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