An essential review of Singapore's response to out-of-hospital cardiac arrests: improvements over a ten-year period.
Alexander E White, Andrew Fw Ho, Nur Shahidah...
https://pubmed.ncbi.nlm.nih.gov/35001113Actively Recruiting
Phase Not Applicable
Age: 21Years +
All Genders
Healthy Volunteers
ID06530433
Evaluation of an Enhanced Community First Responder Support System to Improve Bystander Cardiopulmonary Resuscitation Quality for Patients Experiencing Out-of-hospital Cardiac Arrest
Led by Singapore General Hospital · Updated on 2026-04-13
165
Participants Needed
1
Research Sites
74 weeks
Total Duration
On this page
Sponsors
S
Singapore General Hospital
Lead Sponsor
D
Duke-NUS Graduate Medical School
Collaborating Sponsor
AI-Summary
What this Trial Is About
The trial investigates ways to improve bystander cardiopulmonary resuscitation (CPR) quality for patients experiencing out-of-hospital cardiac arrest (OHCA) in Singapore. Despite many lay responders performing CPR, survival rates with good neurological outcomes have not improved significantly. This research evaluates an enhanced community first responder (CFR) support system using digital technology to provide real-time feedback and communication to improve CPR delivery. Participants are randomized to receive either standard care, where responders use the CPRCard device alone, or the enhanced CFR support system (eCSS), which adds two-way audio and one-way video communication between responders and dispatchers via the CPRCard plus the TCPR Link App and Web. This setup aims to reduce responder stress, encourage alert engagement, and improve CPR quality during resuscitation efforts. Throughout the study, researchers will measure chest compression depth during CPR before handing over to emergency medical services, tracking this for up to 24 hours. Secondary outcomes include survival rates during hospital admission, monitored for up to one year. The study leverages Singapore's robust CFR and OHCA registries, focusing on technology-assisted support and real-time feedback to potentially enhance outcomes for cardiac arrest patients.
CONDITIONS
Brief Title
Enhanced Community First Responder System Evaluation in Singapore
Who Can Participate
Age: 21Years +
All Genders
Healthy Volunteers
Eligibility Criteria
You may qualify if you...
- 18 years old and above
- Registered community first responders with the Singapore Civil Defence Force
- Trial dispatchers with an active account on the myResponder® app on their mobile phones
You will not qualify if you...
- Pregnant community first responders
- Those experiencing any serious physical health conditions
- Those with mental health conditions
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
1
2
3
Your Study Journey
Screening
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Implementation
Duration - Up to 24 hours during out-of-hospital cardiac arrest events
Participants use either the enhanced community first responder support system with two-way audio communication and video streaming or the standard CPRCard device during emergency responses.
Usage during emergency response as needed
Post-event Monitoring
Duration - Up to 1 year following hospital admission
Survivor outcomes are monitored throughout hospital admission to assess discharge rates.
Follow-up assessments as per hospital schedule
Trial Site Locations
Total: 1 location
1
Duke-NUS Medical School
Singapore, Sigapore, Singapore, 169857
Actively Recruiting
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Research Team
F
Fahad J Siddiqui, MSc
A
Alexander A White, MSc
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
HEALTH_SERVICES_RESEARCH
Number of Arms
2
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Published Research Related To This Trial
Long term survival and disease burden from out-of-hospital cardiac arrest in Singapore: a population-based cohort study.
Andrew Fu Wah Ho, Mervyn Jun Rui Lim, Arul Earnest...
https://pubmed.ncbi.nlm.nih.gov/36785853Recent trends in survival from out-of-hospital cardiac arrest in the United States.
Paul S Chan, Bryan McNally, Fengming Tang...
https://pubmed.ncbi.nlm.nih.gov/25399396Effectiveness of bystander cardiopulmonary resuscitation and survival following out-of-hospital cardiac arrest.
E J Gallagher, G Lombardi, P Gennis
https://pubmed.ncbi.nlm.nih.gov/8568985The influence of scenario-based training and real-time audiovisual feedback on out-of-hospital cardiopulmonary resuscitation quality and survival from out-of-hospital cardiac arrest.
Bentley J Bobrow, Tyler F Vadeboncoeur, Uwe Stolz...
https://pubmed.ncbi.nlm.nih.gov/23465553Predictors of survival from out-of-hospital cardiac arrest: a systematic review and meta-analysis.
Comilla Sasson, Mary A M Rogers, Jason Dahl...
https://pubmed.ncbi.nlm.nih.gov/20123673Improved survival after out-of-hospital cardiac arrest is associated with an increase in proportion of emergency crew--witnessed cases and bystander cardiopulmonary resuscitation.
Jacob Hollenberg, Johan Herlitz, Jonny Lindqvist...
https://pubmed.ncbi.nlm.nih.gov/18606920The effect of bystander cardiopulmonary resuscitation on the survival of out-of-hospital cardiac arrests: a systematic review and meta-analysis.
Jianting Song, Wenxiu Guo, Xiaoguang Lu...
https://pubmed.ncbi.nlm.nih.gov/30309373Impact of bystander-focused public health interventions on cardiopulmonary resuscitation and survival: a cohort study.
Audrey L Blewer, Andrew Fu Wah Ho, Nur Shahidah...
https://pubmed.ncbi.nlm.nih.gov/32768435Long-term neurological outcomes in patients after out-of-hospital cardiac arrest.
Youn-Jung Kim, Shin Ahn, Chang Hwan Sohn...
https://pubmed.ncbi.nlm.nih.gov/26826564