Actively Recruiting
Enhanced Problem-solving Therapy and HIV Engagement Support to Improve Perinatal Mental Health & HIV Outcomes in Malawi
Led by University of North Carolina, Chapel Hill · Updated on 2026-04-29
400
Participants Needed
5
Research Sites
170 weeks
Total Duration
On this page
Sponsors
U
University of North Carolina, Chapel Hill
Lead Sponsor
N
National Institute of Mental Health (NIMH)
Collaborating Sponsor
AI-Summary
What this Trial Is About
The main objective of the proposed study is to evaluate the effectiveness of the Enhanced Friendship Bench intervention to improve perinatal depression, HIV care engagement, and infant health outcomes among pregnant women with HIV and depression in Malawi.
CONDITIONS
Official Title
Enhanced Problem-solving Therapy and HIV Engagement Support to Improve Perinatal Mental Health & HIV Outcomes in Malawi
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Presenting for antenatal care at one of the 5 recruitment sites
- 18 years of age or older
- 34 weeks gestation or less
- HIV-positive based on medical records
- Initiating, re-initiating, or on established antiretroviral therapy during the current pregnancy
- Elevated depressive symptoms with a score of 10 or higher on the EPDS screening tool
You will not qualify if you...
- Acute risk due to suicidal thoughts
- Other health concerns requiring emergency response
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 5 locations
1
Area 18 Health Center
Lilongwe, Malawi
Not Yet Recruiting
2
Area 25 Health Center
Lilongwe, Malawi
Actively Recruiting
3
Bwaila Hospital
Lilongwe, Malawi
Actively Recruiting
4
Kawale Health Center
Lilongwe, Malawi
Actively Recruiting
5
Likuni Mission Hosptial
Lilongwe, Malawi
Actively Recruiting
Research Team
B
Brian Pence, PhD, MPH
CONTACT
A
Angela Bengtson, PhD, MA
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
DOUBLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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