Actively Recruiting
Enhanced Recovery After Major Surgery and Chronic Pain for Total Knee Arthroplasty
Led by Hospital for Special Surgery, New York · Updated on 2026-01-15
64
Participants Needed
1
Research Sites
185 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The goal of this interventional clinical trial is to assess opioid consumption 24-48 hrs post anesthesia block among patients undergoing total knee arthroplasty. The main question it aims to answer is: 1\. Is there a difference in opioid consumption 24-48 hours post block administration among patients that receive an adductor canal catheter (ACC) versus adductor canal block (ACB)? Participants will be: * Randomized to receive an adductor canal catheter (ACC) or a sham adductor canal catheter. * Asked to use the Diagnotes application to communicate with the pain doctor while the catheter is in place. * Follow up for up to 6 months post-operation. Researchers will compare the interventional group (ACC) to the control group (sham ACC + ACB) to see if there is difference in opioid consumption and chronic pain at 6 months post-operation.
CONDITIONS
Official Title
Enhanced Recovery After Major Surgery and Chronic Pain for Total Knee Arthroplasty
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients with osteoarthritis scheduled for a primary total knee arthroplasty with a participating surgeon
- Age 18 to 75 years
- Planned use of regional anesthesia
- Ability to follow study protocol
- English speaking
- Patients of participating surgeons: Drs. Mayman, Jerabek, Westrich, Su, Della Valle, Alexiades
- Lives within one hour of the hospital
- Has a smartphone
You will not qualify if you...
- Hepatic or renal insufficiency
- Younger than 18 years old and older than 65
- Patients undergoing general anesthesia
- Allergy or intolerance to one of the study medications
- BMI greater than 40
- Diabetes
- ASA of III or IV
- Chronic gabapentin or pregabalin use for longer than 3 months
- Pain Catastrophizing Scale (PCS) score greater than 30
- Chronic opioid use (longer than 3 months or daily oral morphine equivalent over 5 mg/day for one month)
- Severe valgus deformity or flexion contracture
- Unable to follow home catheter instructions or unwilling to go home with an infusing catheter
- No home caregivers if catheter sent home
- Planned stay at a rehabilitation facility
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
Hospital for Special Surgery
New York, New York, United States, 10021
Actively Recruiting
Research Team
P
Pa Thor, PhD
CONTACT
S
Stavros Memtsoudis, MD/PhD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
DOUBLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
OTHER
Number of Arms
2
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