Actively Recruiting
Enhanced Recovery After Surgery (ERAS) for Complicated Appendicitis
Led by Cedars-Sinai Medical Center · Updated on 2025-04-29
20
Participants Needed
1
Research Sites
44 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The exploratory objective of this pilot study is to evaluate the feasibility and safety of an enhanced recovery protocol that will allow adult patients to be discharged to home on an oral antibiotic regimen for three days following a laparoscopic appendectomy for complicated appendicitis. Feasibility will be determined by high compliance and adherence of patients to the postoperative instructions, while safety will be assessed by the incidence of postoperative infectious complications and requirement for re-admission.
CONDITIONS
Official Title
Enhanced Recovery After Surgery (ERAS) for Complicated Appendicitis
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Individuals between the ages of 18 and 65 years of age.
- Patients undergoing a laparoscopic appendectomy.
- Diagnosis of complicated appendicitis based on pre-operative imaging or intra-operative assessment, including perforated appendicitis without generalized peritonitis, gangrenous appendicitis without generalized peritonitis, suppurative appendicitis, or iatrogenic perforation of the appendix.
- Meet criteria for discharge from the post-anesthesia care unit (PACU).
- Ability to reliably follow up with the study procedures.
You will not qualify if you...
- Age under 18 years or over 65 years.
- Pregnancy.
- Homelessness.
- Patients who present with generalized peritonitis.
- Comorbid conditions including diabetes mellitus, immunosuppressed state for any reason, or patients on chronic anticoagulation (excluding Aspirin 81 mg).
- Patients who present with septic shock.
- Patients who require conversion to an open appendectomy.
- Patients who present with additional findings on imaging or intra-operatively, including ileus or small bowel obstruction.
- Exclusion based on surgeon's clinical judgment.
- Allergy or intolerance to study medications.
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
Cedars-Sinai Medical Center
Los Angeles, California, United States, 90048
Actively Recruiting
Research Team
L
Laura Sarmiento, CCRP
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
TREATMENT
Number of Arms
1
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