Actively Recruiting
Enhanced Recovery After Surgery (ERAS) Total Knee Replacement (TKR) With a Transitional Pain Service
Led by Hospital for Special Surgery, New York · Updated on 2026-04-28
94
Participants Needed
1
Research Sites
419 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
A comparison of two anesthetic techniques for total knee replacements: (1) Peri-Articular Injection (PAI), local infiltration between the popliteal artery and capsule of the knee block (IPACK) and single-shot adductor canal block (ACB) vs. (2) PAI, IPACK and continuous adductor canal block catheter (ACC).
CONDITIONS
Official Title
Enhanced Recovery After Surgery (ERAS) Total Knee Replacement (TKR) With a Transitional Pain Service
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients with osteoarthritis scheduled for a primary total knee arthroplasty with a participating surgeon
- Planned use of regional anesthesia
- Ability to follow study protocol
- English speaking (secondary outcomes include questionnaires validated in English only)
- Lives within one hour of the hospital
- Has a smart phone
You will not qualify if you...
- Hepatic or renal insufficiency
- Younger than 18 years old or older than 65 years old
- Patients undergoing general anesthesia
- Allergy or intolerance to one of the study medications
- BMI greater than 40
- Diabetes
- American Society of Anesthesiologists (ASA) status III or IV
- Chronic gabapentin/pregabalin use longer than 3 months
- Patients with chronic pain or pain catastrophizing scale greater than 30
- Patients with severe valgus deformity or flexion contracture
- Patients unable to follow home catheter instructions or unwilling to go home with an infusing catheter
- Patients without home caregivers if catheter is sent home
- Patients with planned stay at rehab facility
- Non-English speakers (secondary outcomes include questionnaires validated in English only)
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Hospital for Special Surgery
New York, New York, United States, 10023
Actively Recruiting
Research Team
G
George Birch, BS
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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