Actively Recruiting

Phase Not Applicable
Age: 20Years - 40Years
All Genders
Healthy Volunteers
NCT06739148

The Enhancement Effect of Low-Level Laser Therapy for Muscle Training with Combined NMES and BFR

Led by National Cheng-Kung University Hospital · Updated on 2024-12-18

44

Participants Needed

1

Research Sites

43 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Blood flow restriction training (BFR) with neuromuscular stimulation (NMES) is employed for individuals with limited mobility and joint issues. However, this approach is highly susceptible to muscle fatigue, despite its potential beneficial effects on muscle strength. Recently, there has been growing interest in using low-level laser therapy (LLLT) to address muscle fatigue. LLLT, known for improving microcirculation and mitochondrial function, shows promise in alleviating enhanced muscle fatigue associated with combined BFR and NMES training. Despite these positive effects, there is limited knowledge about the short-term training impact of combined BFR and NMES with LLLT preconditioning. This project aims to investigate whether the photobiomodulation effects of LLLT could further enhance the training benefits of combined BFR and NMES. The study will employ an integrated analysis of decomposition surface EMG, EEG, and mechanomyogram to explore the behavior and neuromuscular mechanisms underlying the training benefits. If additional benefits are identified, LLLT pre-conditioning is recommended to enhance the use of combined BFR and NMES.

CONDITIONS

Official Title

The Enhancement Effect of Low-Level Laser Therapy for Muscle Training with Combined NMES and BFR

Who Can Participate

Age: 20Years - 40Years
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Healthy adults aged 20 to 40 years without cardiovascular or neuromusculoskeletal diseases
  • Normal vision range after visual correction
Not Eligible

You will not qualify if you...

  • Students who have a teacher-student relationship with the principal investigator
  • History of brain injury, stroke, spinal cord injury, or other neuromuscular-related conditions
  • Contraindications for laser therapy including pregnancy, malignant tumor tissues, bleeding areas, and photosensitive skin regions
  • Contraindications for blood flow restriction training such as injury or strain in the non-dominant arm's biceps, deep vein thrombosis or venous occlusion in the non-dominant arm, acute unstable fractures, acute regional infections, severe peripheral arterial occlusive disease, complete lymphatic obstruction, or edema due to acute pulmonary edema or congestive heart failure in the non-dominant arm

AI-Screening

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Trial Site Locations

Total: 1 location

1

National Chen Kong University Hospital, Tainan

Tainan, Taiwan

Actively Recruiting

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Research Team

I

Ing-Shiou Hwang, PhD

CONTACT

P

Pei-Fen Li, Master

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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