Actively Recruiting
Enhancement of Quality of Work And Life A Personalized Preventive Work Intervention to Support Sustainable Work Participation in Neurodegenerative Movement Disorders
Led by Radboud University Medical Center · Updated on 2025-05-29
124
Participants Needed
1
Research Sites
N/A
Total Duration
On this page
Sponsors
R
Radboud University Medical Center
Lead Sponsor
A
Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Collaborating Sponsor
AI-Summary
What this Trial Is About
Researchers are investigating how a personalized work intervention called the Preventive Participatory Workplace Intervention PPWI can help people with progressive neurological and neuromuscular disorders keep working. The study focuses on improving work participation and quality of life for individuals with Parkinson Disease, cerebellar ataxia, hereditary spastic paraparesis, and slowly progressive neuromuscular or mitochondrial disorders. This research involves an 18-month randomized controlled trial including 124 Dutch workers. Participants are randomly assigned to either the PPWI group or a usual care group. The PPWI involves a trained facilitator guiding employees and their managers to identify work-related challenges and create agreed-upon solutions to overcome these obstacles. Actions are planned, executed, and evaluated with follow-ups at six months to address new challenges. Usual care continues without restrictions in both groups. During the trial, researchers assess participants at the start and after 6, 12, and 18 months. They measure need for recovery after work, self-efficacy at work, work-related well-being, quality of life, absenteeism, and presenteeism. The study also evaluates cost-effectiveness, the implementation process of the intervention, and its impact mechanisms. Participants will be involved in regular assessments and monitoring throughout the study period.
CONDITIONS
Brief Title
Enhancement of Quality of Work And Life
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Diagnosis of Parkinson Disease, cerebellar ataxia, hereditary spastic paraparesis, or a slowly progressive neuromuscular or mitochondrial disorder confirmed by a treating physician
- Age between 18 and 65 years
- Employed for at least 8 hours per week at baseline
- Intending to continue working during the 18-month study period
- Willing to discuss work-related changes or limitations with employer or manager (disclosing diagnosis not required)
You will not qualify if you...
- Beginning a sick leave procedure under the Gatekeeper Improvement Act
- Fully self-employed (partial self-employment allowed if paid employment is more than half of total hours)
- Having a second employer for more than 8 hours per week
- Insufficient proficiency in the Dutch language
- Severe comorbidity or health issues that prevent following the study, such as severe cognitive impairment, rapid disease progression, or planned surgery
Research Team
P
Pauline van Barschot
E
Elbrich Postma, PhD
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