Actively Recruiting
Enhancing Brain Connectivity in Schizophrenia Through Neuromodulation (Study 1)
Led by The University of Texas Health Science Center, Houston · Updated on 2025-05-18
120
Participants Needed
1
Research Sites
310 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Patients with schizophrenia spectrum disorder (SSD) will be exposed to active repetitive transcranial magnetic stimulation (rTMS) from H coil for improving white matter integrity.
CONDITIONS
Official Title
Enhancing Brain Connectivity in Schizophrenia Through Neuromodulation (Study 1)
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Male and female between 18 and 60 years old
- Able to provide written informed consent
- Diagnosed with schizophrenia spectrum disorder with Evaluation to Sign Consent (ESC) above 10
You will not qualify if you...
- Unable to provide informed consent
- History of seizures
- Acute or unstable major medical illnesses affecting brain function, such as recent stroke, significant head trauma, CNS infection or tumor
- Taking more than 400 mg clozapine per day
- Failed TMS screening questionnaire
- Significant substance use disorder within recent months, excluding nicotine or marijuana dependence
- History or family history of thrombosis or medical conditions increasing blood clot risk
- Pregnant women or women of child-bearing potential not using contraception
- History of head injury with loss of consciousness over 10 minutes or brain surgery
- Unable to avoid alcohol or marijuana use 24 hours before experiments
- Current students or employees of the study lab
- Unable to undergo MRI due to metal implants, devices, or claustrophobia
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
The University of Texas Health Science Center, Houston
Houston, Texas, United States, 77054
Actively Recruiting
Research Team
V
Victoria M Acosta
CONTACT
X
Xiaoming Du, PhD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
TREATMENT
Number of Arms
1
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