Actively Recruiting
Enhancing Brain Connectivity in Schizophrenia Through Neuromodulation (Study 2)
Led by The University of Texas Health Science Center, Houston · Updated on 2025-06-05
120
Participants Needed
1
Research Sites
204 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Patients with schizophrenia spectrum disorder (SSD) will be exposed to active repetitive transcranial magnetic stimulation (rTMS) from H coil combined with cognitive training for improving white matter integrity.
CONDITIONS
Official Title
Enhancing Brain Connectivity in Schizophrenia Through Neuromodulation (Study 2)
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Male and female ages between ages 18-60 years
- Ability to give written informed consent (age 18 or above)
- Diagnosed with schizophrenia-spectrum disorder and Evaluation to Sign Consent (ESC) above 10.
You will not qualify if you...
- Inability to sign informed consent.
- Any history of seizures.
- Any acute and unstable major medical illnesses that may affect normal brain functioning, such as recent stroke, seizure, significant head trauma, CNS infection or tumor, or other significant neurological conditions.
- Taking more than 400 mg clozapine/day and not on anti-seizure medication(s) with sufficient dose.
- Failed TMS screening questionnaire.
- Significant alcohol or other drug use (substance abuse within 1 month or substance dependence history within 6 months and having substance usage within 1 month) other than nicotine or marijuana dependence.
- History of thrombosis, family history of thrombosis, or medical conditions increasing risk of blood clots.
- Woman who is pregnant (child-bearing potential but not on contraceptive and missing menstrual period; or by self-report; or by positive urine pregnancy test).
- History of head injury with loss of consciousness over 10 minutes; history of brain surgery.
- Cannot refrain from using alcohol and/or marijuana 24 hours or more prior to experiments.
- Students and employees currently involved with the lab.
- Unable to undergo MRI scanning due to metallic devices or claustrophobia.
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
The University of Texas Health Science Center, Houston
Houston, Texas, United States, 77054
Actively Recruiting
Research Team
B
Bhim M Adhikari
CONTACT
X
Xiaoming Du, PhD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
TREATMENT
Number of Arms
1
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