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ID06285708

Testing Enhanced Prolonged Exposure Therapy with Crisis Response Plan for Adults with PTSD and Suicidal Thoughts

Led by Ohio State University · Updated on 2026-06-29

100

Participants Needed

1

Research Sites

26 weeks

Total Duration

AI-Summary

What this Trial Is About

This research aims to reduce suicidal thoughts and behaviors among people seeking treatment who have posttraumatic stress disorder PTSD. It compares the effectiveness of prolonged exposure PE therapy combined with a crisis response plan CRP versus PE with a self-guided safety plan, which is considered standard care. The study addresses a gap in knowledge by evaluating these treatments together to better understand their impact on suicide risk in individuals with PTSD. Participants receive prolonged exposure therapy, a cognitive behavioral treatment involving imaginal exposure, in-vivo exposure, psychoeducation, and controlled breathing. Unlike typical weekly sessions, this study delivers daily 60-minute sessions for 10 consecutive weekdays over two weeks. One group completes a CRP collaboratively with their clinician during the first session, while the other group completes a self-guided safety plan. Both plans include strategies for managing suicidal crises but differ in involvement and content. Throughout the study and up to one year afterward, participants are assessed using self-report tools and interviews measuring suicidal thoughts, behaviors, and PTSD symptoms. Researchers monitor changes using instruments like the Beck Scale for Suicidal Ideation and the PTSD Checklist for DSM-5. Additional questionnaires evaluate emotional regulation, hopelessness, and other psychological factors. This ongoing follow-up helps understand treatment effects and safety over time.

CONDITIONS

Brief Title

Enhancing the Effectiveness of Prolonged Exposure Among Suicidal Individuals With PTSD

Research Team

J

Jaryd Hiser, Ph.D.

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