Actively Recruiting
Enhancing the Effectiveness of Prolonged Exposure Among Suicidal Individuals With PTSD
Led by Ohio State University · Updated on 2026-04-03
100
Participants Needed
1
Research Sites
113 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The long-term goal of this study is to reduce suicidal thoughts and behaviors among treatment-seeking individuals who also have posttraumatic stress disorder (PTSD). Prolonged exposure (PE) and crisis response plan (CRP) have demonstrated empirical support for reducing suicide attempts as compared to treatment as usual. However, no studies to date have assessed their effectiveness when used in combination. In light of this knowledge gap, the primary objective of this study will be to test the effectiveness of PE augmented with CRP as compared to PE with care as usual (self-guided treatment plan), an active comparator, for the reduction of suicide ideations and attempts for individuals with comorbid PTSD.
CONDITIONS
Official Title
Enhancing the Effectiveness of Prolonged Exposure Among Suicidal Individuals With PTSD
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Current diagnosis of PTSD or subthreshold PTSD
- Ability to speak and understand the English language
- Ability to complete the informed consent process
You will not qualify if you...
- Substance use disorder requiring medical management
- Imminent suicide risk warranting inpatient hospitalization or suicide-focused treatment
- Impaired mental status that precludes the ability to provide informed consent (e.g., intoxication, psychosis, mania)
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
The Ohio State University
Columbus, Ohio, United States, 43210
Actively Recruiting
Research Team
J
Jaryd Hiser, Ph.D.
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here