Actively Recruiting
Led by Washington University School of Medicine · Updated on 2025-06-27
1000
Participants Needed
1
Research Sites
43 weeks
Total Duration
W
Washington University School of Medicine
Lead Sponsor
U
University of Abuja Teaching Hospital
Collaborating Sponsor
Researchers are evaluating a program aimed at improving heart health for pregnant women with obesity and their children in Abuja, Nigeria. This study focuses on how a home-visit intervention based on the Parents as Teachers curriculum combined with a Healthy Eating Active Living program may help women and their children adopt healthier lifestyles to promote cardiovascular health. The study aims to compare weight changes and lifestyle behaviors between women who receive the intervention and those who do not. Participants will be randomly assigned to one of two groups. One group will receive 40 biweekly home visits that deliver the PAT+HEALTH curriculum, focusing on lifestyle and behavioral changes to support heart health during pregnancy and after childbirth. The control group will receive standard prenatal and postnatal care without the additional intervention. The program is led by community health educators and covers both prenatal and postnatal periods. Participants will complete surveys and have clinical, laboratory, and body measurements taken at the start of the study, at birth, and every six months for two years after delivery. Researchers will monitor changes in maternal weight, cardiovascular health scores, lifestyle behaviors such as diet and physical activity, and child health outcomes. The study includes safety tracking for maternal and child health events throughout the follow-up period, which lasts up to 24 months post-delivery.
CONDITIONS
Enhancing Intergenerational Health in Nigeria: Peripartum as Critical Life Stage for Cardiovascular Health
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Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - Approximately 18 months from early pregnancy through postnatal period
Participants randomized to the intervention arm will receive 40 biweekly sessions of the PAT+HEALTH behavioral intervention focusing on cardiovascular health during pregnancy and after birth. Those in the control group will receive standard ante- and postnatal care.
Biweekly visits for up to 18 months
Total: 1 location
1
University of Abuja Teaching Hospital
Abuja, Nigeria
Actively Recruiting
M
Mark D Huffman, MD, MPH
G
Guhan R Iyer, MPH
Study Type
INTERVENTIONAL
Masking
TRIPLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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