Actively Recruiting
Enhancing Intergenerational Health in Nigeria: Peripartum as Critical Life Stage for Cardiovascular Health
Led by Washington University School of Medicine · Updated on 2025-06-27
1000
Participants Needed
1
Research Sites
162 weeks
Total Duration
On this page
Sponsors
W
Washington University School of Medicine
Lead Sponsor
U
University of Abuja Teaching Hospital
Collaborating Sponsor
AI-Summary
What this Trial Is About
The purpose of the ENHANCE-CVH study is to promote intergenerational cardiovascular health (CVH) of women and children in Abuja and the surrounding Federal Capital Territory of Nigeria. The study team plans to achieve this through an adaptation of an existing evidence based intervention - Parents as Teachers (PAT) curriculum + Healthy Eating Active Living Taught at Home (HEALTH) - among pregnant women with obesity and their children in Nigeria. The aim of the study is to evaluate the effectiveness and implementation of community health educator-led delivery of the PAT+HEALTH intervention via home visits to answer the following main questions: * Will the women participating in the intervention have a greater change in weight from baseline to 18-month follow up compared to the women who do not? * Will the women and children in the intervention group display better CVH promoting lifestyle behaviors compared to those in the control group? Participants in the study will complete baseline surveys and have clinical data, lab data, and body measurements captured. Participants will also have these procedures repeated at birth and every 6 months up to 24 months post-delivery. Once randomized to the intervention group, participants will complete 40 biweekly PAT+HEALTH curriculum delivery sessions, each lasting approximately 60-90 minutes.
CONDITIONS
Official Title
Enhancing Intergenerational Health in Nigeria: Peripartum as Critical Life Stage for Cardiovascular Health
Who Can Participate
Eligibility Criteria
You may qualify if you...
- 18 years of age or older
- Pregnant women under 14 weeks gestation
- Singleton pregnancy
- Body mass index over 30 kg/m2
- Willing to participate in the study for 2 years
- Planning to receive prenatal care and deliver at participating healthcare centers or University of Abuja Teaching Hospital
- Able to give informed consent for participation for herself and her child
You will not qualify if you...
- Currently enrolled in a weight loss program
- Unable to participate in a walking program
- Active substance abuse
- Taking medications that affect weight (e.g., corticosteroids, antipsychotics)
- Planning to move away within the next 2 years
- Unwilling to provide informed consent
AI-Screening
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Trial Site Locations
Total: 1 location
1
University of Abuja Teaching Hospital
Abuja, Nigeria
Actively Recruiting
Research Team
M
Mark D Huffman, MD, MPH
CONTACT
G
Guhan R Iyer, MPH
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
TRIPLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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