Actively Recruiting
Enhancing Language Function in Aphasia
Led by University of Arizona · Updated on 2024-12-09
30
Participants Needed
1
Research Sites
319 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Aphasia is an acquired impairment of language, that commonly results from damage to language areas in the brain (typically the left side of the brain). This impairment is seen in many aspects of language, including understanding, speaking, reading and writing. It is estimated that about 2 million individuals are currently living with aphasia in the United States. Further, about 200,000 Americans acquire aphasia every year (National Aphasia Association, 2020). Aphasia poses significant impact on the affected individuals and their families. Behavioral treatments that target language deficits have been shown to enhance overall communication skills and life satisfaction among individuals with aphasia. Although there is evidence that suggests that treatment is efficacious for individuals with aphasia, the extent of improvement long-term coupled with the neural patterns among those individuals are largely unknown. The current study aims to investigate the efficacy of language-based treatment and its corresponding neural patterns.
CONDITIONS
Official Title
Enhancing Language Function in Aphasia
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Present with speech-language impairment (aphasia) caused by stroke or dementia
- Have a medical diagnosis of primary progressive aphasia (PPA) by a neurologist or physician
- Are native speakers of English
- Have no contraindications for MRI
- Have adequate (normal or corrected to normal) vision and hearing
You will not qualify if you...
- Diagnosed with mood, anxiety, psychotic, or substance abuse disorders
- Have highly magnetizable metallic implants affecting MRI image quality
- Have neurological disorders other than those studied, such as epilepsy, Multiple Sclerosis, or Parkinson's Disease
- Have contraindications for MRI including pacemakers, metallic cardiac pumps, valves, magnetic materials, implanted electronic pumps, or other conditions preventing exposure to magnetic fields
- Suffer from clinically significant claustrophobia
- Have severe systemic disease like renal failure
- Are in poor overall health
- Are pregnant
- Have had epileptic activity in the past 12 months
- Have a personal or family history of epilepsy or other seizure disorders
- Have had brain surgery in the past
- Have implanted metallic skull plates or intracranial implants
- Have skin lesions or skull damage
- Have a history of excessive alcohol or drug use
- Have premorbid psychiatric disease affecting communication
- Have severe non-linguistic cognitive disturbances that interfere with language therapy
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
University of Arizona
Tucson, Arizona, United States, 85721-0071
Actively Recruiting
Research Team
A
Aneta Kielar, PhD
CONTACT
F
Fatima Jebahi, MS
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
TRIPLE
Allocation
RANDOMIZED
Model
FACTORIAL
Primary Purpose
TREATMENT
Number of Arms
2
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