Actively Recruiting

Phase Not Applicable
Age: 45Years - 80Years
All Genders
NCT04920318

Enhancing Language Function in Primary Progressive Aphasia

Led by University of Arizona · Updated on 2024-11-29

20

Participants Needed

1

Research Sites

302 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This study's goal is to use non-invasive brain stimulation (NBS) techniques to treat language impairment associated with Primary Progressive Aphasia (PPA). The purpose of this study is to combine behavioral language intervention with individualized noninvasive brain stimulation techniques, called transcranial direct current stimulation (tDCS) to help the brain reorganize around damage and improve language functions.

CONDITIONS

Official Title

Enhancing Language Function in Primary Progressive Aphasia

Who Can Participate

Age: 45Years - 80Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Diagnosed with Primary Progressive Aphasia by a neurologist or speech-language pathologist
  • Having a speech-language deficit caused by Primary Progressive Aphasia
  • Native speaker of English or equivalent proficiency
  • Adequate vision (normal or corrected to normal)
  • Adequate hearing
Not Eligible

You will not qualify if you...

  • Diagnosed with mood, anxiety, psychotic, or substance abuse disorders according to DSM-IV criteria
  • Having highly magnetizable metallic implants or certain dental work
  • Diagnosed with neurological disorders other than PPA, such as epilepsy, Multiple Sclerosis, or Parkinson's Disease
  • Having contraindications for MRI
  • Having pacemakers, metallic cardiac pumps, valves, or magnetic surgical clips
  • Experiencing clinically significant claustrophobia
  • Having severe systemic diseases like renal failure or poor general health
  • Being pregnant
  • Having epileptic activity in the past 12 months or a family history of epilepsy or seizure disorders
  • History of brain surgery
  • Having metallic skull plates or implants
  • Having skin lesions or skull damage
  • Excessive use of alcohol or drugs
  • Premorbid psychiatric disease affecting communication
  • Severe non-linguistic cognitive disturbances that interfere with language therapy

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

University of Arizona

Tucson, Arizona, United States, 85721-0071

Actively Recruiting

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Research Team

A

Aneta Kielar, PhD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

TRIPLE

Allocation

RANDOMIZED

Model

CROSSOVER

Primary Purpose

TREATMENT

Number of Arms

2

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