Actively Recruiting
Enhancing Memory in CPT for PTSD
Led by VA Office of Research and Development · Updated on 2025-10-14
30
Participants Needed
1
Research Sites
89 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Several psychotherapies for posttraumatic stress disorder (PTSD) have a strong evidence base for their efficacy, but nonresponse rates are high, particularly among older Veterans. Accumulating evidence indicates that memory deficits and poor learning of therapy contents adversely affect psychotherapy treatment response in PTSD. However, limited research has examined methods for increasing learning of therapy contents in psychotherapy for PTSD. The proposed study aims to examine the feasibility of integrating an intervention to increase learning and memory of psychotherapy content into the provision of a widely used psychotherapy, cognitive processing therapy (CPT), for older adults with PTSD. The ultimate goal of this line of research is to develop novel rehabilitation interventions to increase functioning for individuals with PTSD.
CONDITIONS
Official Title
Enhancing Memory in CPT for PTSD
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Veterans with DSM-5 diagnoses of PTSD via the Clinician Administered PTSD Scale (CAPS-5)
- Age >59
You will not qualify if you...
- Daily benzodiazepine use due to memory impairing effects
- Bipolar or psychotic disorders
- Current suicidal ideation with plan or intent
- Current moderate or severe substance use disorder not in remission for more than 1 month
- Severe traumatic brain injury
- Montreal Cognitive Assessment (MoCA) score indicative of dementia
- Other disorders that would severely limit study participation
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Corporal Michael J. Crescenz VA Medical Center, Philadelphia, PA
Philadelphia, Pennsylvania, United States, 19104-4551
Actively Recruiting
Research Team
J
James C Scott, PhD
CONTACT
R
Richard A Moore
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
TRIPLE
Allocation
RANDOMIZED
Model
SINGLE_GROUP
Primary Purpose
TREATMENT
Number of Arms
2
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