Actively Recruiting

Phase 2
Age: 45Years - 75Years
All Genders
NCT05839535

Enhancing Modulation Effects of Baduanjin Through Neuromodulation for Knee OA

Led by Massachusetts General Hospital · Updated on 2025-05-07

140

Participants Needed

1

Research Sites

234 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This study will combine brain imaging and neuromodulation tools to investigate the underlying neurobiological mechanisms of exercises. The findings will enhance our understanding of the mechanisms underlying mind-body exercise and facilitate the development of new pain management approaches.

CONDITIONS

Official Title

Enhancing Modulation Effects of Baduanjin Through Neuromodulation for Knee OA

Who Can Participate

Age: 45Years - 75Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Volunteers 45-75 years of age
  • Meet the American College of Rheumatology criteria for knee osteoarthritis for at least 3 months
  • Physically able to participate in Baduanjin and stretching programs
  • Willing to complete the 12-week study
  • Able to participate in MRI scans
  • Able to read and understand English well enough to answer assessment questions
Not Eligible

You will not qualify if you...

  • Regularly practiced Baduanjin, Tai Chi, Yoga, physical therapy, or routine exercise in the past year
  • Serious medical conditions limiting participation, such as symptomatic heart or lung disease needing oxygen, uncontrolled metabolic diseases, severe kidney or liver disease
  • Received steroid injections or reconstructive surgery on the affected knee in the past 3 months, or hyaluronic acid injections in the past 6 months
  • Mini-Mental Status Examination score below 24
  • Unable to walk without a cane or assistive device
  • Plans to have surgery during the study
  • Plans to move away permanently during the study period

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Massachusetts General Hospital

Charlestown, Massachusetts, United States, 02129

Actively Recruiting

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Research Team

J

Jian Kong

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

DOUBLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

OTHER

Number of Arms

4

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