Actively Recruiting
Enhancing Physical Reserve to Promote Resilience in Physically Frail Older Adults
Led by The Hong Kong Polytechnic University · Updated on 2026-04-07
224
Participants Needed
1
Research Sites
166 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The goal of this clinical trial is to assess the efficacy of combined aerobic and resistance training in enhancing physical reserve in older adults with physical frailty. Investigator contend that enhanced physical reserve will enable preservation of cognitive and physical function. The main questions aims to answer are: (1) Compared with usual care (i.e., CON), will 3-month aerobic and resistance training (ATRT) improve physical reserve in older adults with physical frailty? (2) Compared with CON, will ATRT lead to changes in the neural network organization? (3) Will improved physical reserve lead to better maintenance of cognitive and physical functioning in spite of presence of white matter hyperintensities (WMH)?
CONDITIONS
Official Title
Enhancing Physical Reserve to Promote Resilience in Physically Frail Older Adults
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Community-dwelling adults (not living in nursing or extended care units)
- Scored less than 9 out of 12 on the Short Physical Performance Battery (SPPB)
- Scored more than 18 out of 30 on the Montreal Cognitive Assessment (MoCA)
- Able to walk independently; use of walking aids is allowed
- Safe to exercise as confirmed by the Physical Activity Readiness Questionnaire Plus and a physician
- Have internet access at home
- Able to provide written informed consent
You will not qualify if you...
- Diagnosed with dementia or stroke
- Engaged in strength and balance training exercises more than twice per week in the past 3 months
- Unable to understand, speak, and read Cantonese, Chinese, or English proficiently
- Have contraindications for MRI such as MRI-incompatible implants
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
The Hong Kong Polytechnic University, Department of Rehabilitation Sciences
Hong Kong, Hong Kong, Hong Kong, 0000000
Actively Recruiting
Research Team
C
Chun Liang HSU, PhD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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