Actively Recruiting

Phase 4
Age: 18Years +
MALE
Healthy Volunteers
NCT07218211

Enhancing PrEP Uptake and Retention Among Latine TGW and GBM in the South Using Long-Acting Injectable PrEP

Led by Duke University · Updated on 2026-02-02

100

Participants Needed

1

Research Sites

103 weeks

Total Duration

On this page

Sponsors

D

Duke University

Lead Sponsor

G

Gilead Sciences

Collaborating Sponsor

AI-Summary

What this Trial Is About

The purpose of this project is to test a culturally-tailored, community-delivered long-acting injectable PrEP (lenacapavir) program for Latine gay and bisexual men (GBM) and transgender women (TGW). The objective is to evaluate whether this intervention demonstrates greater persistence on lenacapavir for Latine GBM and TGW compared with what has been observed historically at the Duke PrEP Clinic.

CONDITIONS

Official Title

Enhancing PrEP Uptake and Retention Among Latine TGW and GBM in the South Using Long-Acting Injectable PrEP

Who Can Participate

Age: 18Years +
MALE
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Assigned male sex at birth
  • Report sexual activity with someone assigned male at birth or identify as gay, bisexual man or transgender woman
  • Identify as Hispanic and/or Latine
  • Able to provide informed consent in English or Spanish
  • At least 18 years old
  • Weigh at least 77 lbs (35 kg) by self-report
  • Interested in PrEP and willing to follow study procedures
Not Eligible

You will not qualify if you...

  • Living with HIV
  • Assigned female sex at birth
  • Currently taking oral PrEP from another source and unwilling to switch to lenacapavir for study duration
  • History of severe kidney or liver disease or clinical signs of these diseases
  • Taking medications that significantly interact with lenacapavir

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

El Centro Hispano

Durham, North Carolina, United States, 27701

Actively Recruiting

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Research Team

I

Iris Navarro Clinical Research Coordinator

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

PREVENTION

Number of Arms

1

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