Actively Recruiting
Enhancing Recovery in Non-Traumatic Spinal Cord Injury
Led by Western University, Canada · Updated on 2024-03-28
40
Participants Needed
1
Research Sites
410 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The investigators have spent the last decade uncovering unique metabolic and functional abnormalities in the brains of patients with spinal cord compression. Degenerative spinal cord compression represents a unique model of reversible spinal cord injury. In the investigator's previous work, they have demonstrated that cortical reorganization and recruitment is associated with metabolic changes in the brains of patients recovering from spinal cord compression and is correlated with recovery and improved neurological scores. The goal of this study is to combine a rigorous platform of clinical care that includes preoperative evaluation, surgery, and rehabilitation, with state of the art imaging techniques to demonstrate how rehabilitative therapy can increase brain plasticity and recovery of neurological function in patients with spinal cord injury. Neurological function will be carefully evaluated in two groups of patients, those receiving rehabilitation and those not receiving rehabilitation after spine surgery, and will be correlated with the results of advanced imaging.
CONDITIONS
Official Title
Enhancing Recovery in Non-Traumatic Spinal Cord Injury
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Right-handed
- History of progressive neurological deficits less than 24 months
- Eligible for MRI scanning
You will not qualify if you...
- Having any other neurological disorder or systemic disease that can impair neurological function
- Not fluent in reading and speaking English
- Being claustrophobic
- Unable to follow simple task instructions and maintain standardized movements
- Being unable to return for all follow-up imaging and rehabilitation sessions
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
LHSC - University Hospital
London, Ontario, Canada, N6A 5A5
Actively Recruiting
Research Team
S
Sarah Detombe, PhD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
DOUBLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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