Actively Recruiting
Enhancing Transdiagnostic Mechanisms of Cognitive Dyscontrol (R33)
Led by University of California, San Diego · Updated on 2025-10-24
128
Participants Needed
1
Research Sites
147 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The proposed project aims to test the cognitive and neural effects of a cognitive training in a sample of individuals seeking treatment for anxiety, depression, or traumatic stress symptoms. Participants will be randomly assigned to one of two groups. Group 1 will receive a computer-based program that is designed as a cognitive training intervention and Group 2 will receive a similar computer-based exercise that researchers think will be less effective in training thinking skills (also known as a control or sham condition). Participants will be compared on cognitive performance and brain response during cognitive tasks from baseline to post-treatment.
CONDITIONS
Official Title
Enhancing Transdiagnostic Mechanisms of Cognitive Dyscontrol (R33)
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age between 21 and 55 years
- Fluent in English
- Diagnosed with mood, anxiety, or traumatic stress disorder
- Clinically elevated repetitive negative thinking
- Outpatient status
- Stable selective serotonin reuptake inhibitor (SSRI) medication use for at least 6 weeks if applicable
You will not qualify if you...
- Diagnosis of severe alcohol or moderate or greater substance use disorder within the past year
- Lifetime history of psychotic or bipolar I disorder
- Acute suicidality requiring immediate clinical intervention
- Neurodegenerative or neurodevelopmental disorders
- History of moderate or severe traumatic brain injury or other neurological conditions
- Sensory deficits preventing completion of study tasks
- Conditions that make MRI scanning unsafe, such as metal in the body
- Current pregnancy
- Currently receiving psychosocial treatment
- Currently taking psychiatric medications other than SSRIs
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
UC San Diego
San Diego, California, United States, 92037
Actively Recruiting
Research Team
J
Jessica Bomyea, Ph.D.
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
DOUBLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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