Actively Recruiting

Phase Not Applicable
Age: 65Years +
All Genders
NCT06313853

Enhancing Triadic Communication About Cognition for Older Adults With Alzheimer's Disease or Related Dementias Facing a Cancer Management Decision

Led by University of Rochester · Updated on 2026-03-24

300

Participants Needed

1

Research Sites

134 weeks

Total Duration

On this page

Sponsors

U

University of Rochester

Lead Sponsor

N

National Institute on Aging (NIA)

Collaborating Sponsor

AI-Summary

What this Trial Is About

Building upon prior work, the investigator team developed a communication intervention for older adults with ADRD who are considering a decision about cancer management (adapted intervention: COACH-Cog). The investigators hypothesize that for patients with dual diagnoses of ADRD and cancer, COACH-Cog will increase autonomy support of care partners and patients in the decision-making process, leading to greater acknowledgement and support of cognitive concerns and cognitive-related goals, thereby improving goal concordant care. The investigators are conducting a pilot randomized controlled trial (RCT; cluster randomized by physician) including approximately 45 oncology clinicians and 130 patient/care partner dyads evaluating the effect of COACH-Cog on care partner and patient autonomy support, care partner well-being, goal-concordance, and communication.

CONDITIONS

Official Title

Enhancing Triadic Communication About Cognition for Older Adults With Alzheimer's Disease or Related Dementias Facing a Cancer Management Decision

Who Can Participate

Age: 65Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Be age 65 or older
  • Have a clinical diagnosis of Alzheimer's disease or related dementia (including Alzheimer's disease, vascular dementia, Lewy body dementia, frontotemporal dementia, or dementia of unknown subtype)
  • Have a clinical diagnosis of cancer of any type or stage
  • Expect a potential decision about cancer-related management as confirmed by the primary medical oncology clinician
  • Have a care partner willing and able to participate in the study
  • Be able to read and understand English
  • Be able to provide informed consent or have a legally authorized representative to provide consent
  • Care partners must be age 18 or over, able to read and understand spoken English, and able to provide informed consent
  • Oncology clinicians must be affiliated with the Wilmot Cancer Institute and not planning to move or retire within 2 years
Not Eligible

You will not qualify if you...

History of severe allergic reactions to study medication Currently pregnant or breastfeeding Recent participation in another clinical trial within the last 30 days Presence of uncontrolled medical conditions that could affect safety

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Trial Site Locations

Total: 1 location

1

University of Rochester Wilmot Cancer Institute

Rochester, New York, United States, 14620

Actively Recruiting

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Research Team

A

Allison Magnuson

CONTACT

J

Jessica Bauer

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

DOUBLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

SUPPORTIVE_CARE

Number of Arms

2

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