Study of Oral Sodium Dihydrogen Phosphate and Disodium Hydrogen Phosphate Granules to Treat Low Blood Phosphorus Levels in Adults Aged 18 to 80

What this Trial Is About

Researchers are evaluating the effectiveness and safety of Sodium Dihydrogen Phosphate and Disodium Hydrogen Phosphate Granules for treating people with mild, moderate, or severe hypophosphatemia, a condition where blood phosphate levels are low. The study aims to find out whether taking these phosphate supplements by mouth or through a feeding tube can increase blood phosphorus levels and whether this treatment causes any digestive side effects. Participants are given daily doses of phosphate granules based on how severe their hypophosphatemia is mild cases get a lower dose, moderate cases a medium dose, and severe cases a higher dose, all calculated by body weight. The treatment lasts up to 14 days. Each morning, blood samples are taken to measure phosphorus levels, and doctors adjust the dose depending on how the levels change. Throughout the study, participants blood phosphorus and gastrointestinal symptoms are closely monitored. Researchers also track how quickly phosphorus levels normalize and any side effects or intolerances to the treatment. Scores related to illness severity are recorded at the start and end of the study. The total involvement lasts up to 14 days, with daily assessments to evaluate the treatments effects and safety.

Enteral Supplementation With Sodium Dihydrogen Phosphate and Disodium Hydrogen Phosphate Granules for the Treatment of Hypophosphatemia.