Actively Recruiting

Age: 1Year - 17Years
All Genders
NCT06659393

Entresto Tablets and Granules for Pediatric Specified Drug-use Survey (Pediatric Chronic Heart Failure)

Led by Novartis Pharmaceuticals · Updated on 2026-04-13

30

Participants Needed

28

Research Sites

153 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This is multicenter, single-arm, non-interventional, centrally enrolled specified drug-use survey to investigate the safety of Entresto Tablets or Entresto Granules for Pediatric in pediatric patients with chronic heart failure in actual clinical settings for up to 52 weeks after administration.

CONDITIONS

Official Title

Entresto Tablets and Granules for Pediatric Specified Drug-use Survey (Pediatric Chronic Heart Failure)

Who Can Participate

Age: 1Year - 17Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Written informed consent by a legally acceptable representative must be obtained before the start of treatment with Entresto.
  • Patients who received Entresto for the first time under the indication of chronic heart failure
  • Pediatric patients aged 1 to < 18 years old at the start of treatment with Entresto
Not Eligible

You will not qualify if you...

  • Patients who have received drugs containing the same ingredient as Entresto (including investigational products and drugs for post-marketing clinical study)
  • Patients with a history of hypersensitivity to any ingredients of Entresto
  • Patients currently under treatment with angiotensin-converting enzyme inhibitors or within 36 hours of discontinuation of such treatment
  • Patients with a history of angioedema (including angioedema due to angiotensin II receptor blockers or angiotensin-converting enzyme inhibitors, hereditary angioedema, acquired angioedema, and idiopathic angioedema)
  • Patients with diabetes mellitus under treatment with aliskiren fumarate (except those with markedly poorly controlled blood pressure despite other antihypertensive therapies)
  • Patients with severe hepatic impairment (Child-Pugh class C)
  • Pregnant women or women who may be pregnant

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 28 locations

1

Novartis Investigative Site

Ōbu, Aichi-ken, Japan, 474 8710

Actively Recruiting

2

Novartis Investigative Site

Toyoake, Aichi-ken, Japan, 4701192

Actively Recruiting

3

Novartis Investigative Site

Kurume, Fukuoka, Japan, 830-0011

Actively Recruiting

4

Novartis Investigative Site

Kurume, Fukuoka, Japan, 830-8543

Actively Recruiting

5

Novartis Investigative Site

Sapporo, Hokkaido, Japan, 060-8648

Actively Recruiting

6

Novartis Investigative Site

Tsukuba, Ibaraki, Japan, 3058576

Actively Recruiting

7

Novartis Investigative Site

Kawasaki, Kanagawa, Japan, 2168511

Actively Recruiting

8

Novartis Investigative Site

Yokohama, Kanagawa-ku, Japan, 236-0004

Actively Recruiting

9

Novartis Investigative Site

Tsu, Mie-ken, Japan, 514-8507

Actively Recruiting

10

Novartis Investigative Site

Nagasaki, Nagasaki, Japan, 852-8501

Actively Recruiting

11

Novartis Investigative Site

Ōmura, Nagasaki, Japan, 856-8562

Actively Recruiting

12

Novartis Investigative Site

Hidaka, Saitama, Japan, 350-1298

Actively Recruiting

13

Novartis Investigative Site

Saitama, Saitama, Japan, 330-8777

Actively Recruiting

14

Novartis Investigative Site

Hamamatsu, Shizuoka, Japan, 430-8558

Actively Recruiting

15

Novartis Investigative Site

Bunkyo Ku, Tokyo, Japan, 113-8655

Actively Recruiting

16

Novartis Investigative Site

Bunkyo Ku, Tokyo, Japan, 1138431

Actively Recruiting

17

Novartis Investigative Site

Bunkyo-ku, Tokyo, Japan, 113-8603

Actively Recruiting

18

Novartis Investigative Site

Fuchū, Tokyo, Japan, 183-0003

Actively Recruiting

19

Novartis Investigative Site

Fuchū, Tokyo, Japan, 1838561

Actively Recruiting

20

Novartis Investigative Site

Ōta-ku, Tokyo, Japan, 143 8541

Actively Recruiting

21

Novartis Investigative Site

Setagaya-ku, Tokyo, Japan, 1578535

Actively Recruiting

22

Novartis Investigative Site

Shinagawa-ku, Tokyo, Japan, 1428666

Actively Recruiting

23

Novartis Investigative Site

Shinjuku Ku, Tokyo, Japan, 1628666

Actively Recruiting

24

Novartis Investigative Site

Toyama, Toyama, Japan, 9300194

Actively Recruiting

25

Novartis Investigative Site

Akita, Japan, 010-8543

Actively Recruiting

26

Novartis Investigative Site

Fukuoka, Japan, 8128582

Active, Not Recruiting

27

Novartis Investigative Site

Kumamoto, Japan, 862-8505

Completed

28

Novartis Investigative Site

Okayama, Japan, 7008558

Actively Recruiting

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Research Team

N

Novartis Pharmaceuticals

CONTACT

N

Novartis Pharmaceuticals

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

0

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