Actively Recruiting
Environmental and Behavioral Factors in Infertility and ART Outcomes
Led by The Third Xiangya Hospital of Central South University · Updated on 2026-02-03
5000
Participants Needed
1
Research Sites
526 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This large-scale study aims to understand how everyday environment and lifestyle may affect the success of fertility treatments like IVF. The main idea is that exposure to certain environmental chemicals (e.g., from plastics or air pollution) and personal habits (e.g., diet, stress) could be linked to whether these treatments result in a successful pregnancy and live birth. The study will follow approximately 5,000 couples undergoing fertility treatment in Hunan, China. Participants will answer questionnaires about their health, lifestyle, and environment and provide small biological samples (like blood and urine) during their standard treatment process. Their treatment outcomes will be tracked anonymously.The goal is to identify factors that might lower the chances of treatment success. This knowledge could help future patients and doctors make informed decisions and could guide public health advice on reducing potential risks. The study has received ethical approval, and all participant information will be kept strictly confidential.
CONDITIONS
Official Title
Environmental and Behavioral Factors in Infertility and ART Outcomes
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Women aged 18 to 46 using their own eggs
- Men aged 18 to 55 using their own sperm
- Diagnosed with infertility
- Medical history clearly showing duration of infertility
- Voluntarily agree to participate and sign informed consent
You will not qualify if you...
- Female with sperm-egg combination disorder caused by tubal factors
- Female with acute reproductive or urinary infections or sexually transmitted diseases
- Female with genetic diseases, severe physical illness, or mental disorders
- History of giving birth to infants with congenital defects caused by the female
- Female exposed to teratogenic radiation, toxins, or drugs currently active
- Female with alcoholism or drug abuse
- Either partner with acute reproductive or urinary infections or sexually transmitted diseases
- Either partner with active exposure to teratogenic radiation, toxins, or drugs
- Female egg or embryo donor partner with acute infections or sexually transmitted diseases or alcoholism/drug abuse
- Female with unviable uterus or severe physical illnesses preventing pregnancy
- No embryo transfer after egg retrieval
- More than 180 days passed since egg retrieval and frozen embryo transfer performed
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Reproductive Medicine Center of Xiangya Third Hospital of Central South University
Changsha, Hunan, China, 410013
Actively Recruiting
Research Team
X
Xingping Zhao
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
2
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