Actively Recruiting
Ephedrine for Reducing Onset Time of Rocurinium in Elderly Patients
Led by Matias Vested · Updated on 2025-01-17
80
Participants Needed
2
Research Sites
46 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The aim of this study is to determine the onset time of rocuronium after administration of ephedrine 0.15 mg/kg in patients with age ≥ 80 years. The hypothesis of this study is that ephedrine 0.15 mg/kg provides a shorter onset time compared to placebo (saline).
CONDITIONS
Official Title
Ephedrine for Reducing Onset Time of Rocurinium in Elderly Patients
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age 80 years or older
- Scheduled for elective operations under general anesthesia with intubation
- American Society of Anesthesiologists (ASA) physical status classification I to III
- Able to give informed consent
- Able to read and understand Danish
You will not qualify if you...
- Known allergy to rocuronium or ephedrine
- Neuromuscular disease that may interfere with neuromuscular data
- Need for rapid sequence induction
- Daily use of beta-blocking agents
- Known cardiac arrhythmia such as atrial fibrillation, supraventricular, or ventricular arrhythmia
AI-Screening
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Trial Site Locations
Total: 2 locations
1
Department of Anaesthesiology, Pain and Respiratory Support, Rigshospitalet Glostrup
Copenhagen, Denmark, 2100
Actively Recruiting
2
Department of Anesthesia, Centre of Head and Orthopedics, 6013 Rigshospitalet
Copenhagen, Denmark, 2100
Actively Recruiting
Research Team
M
Matias Vested, MD, PhD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
TRIPLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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