Actively Recruiting
Epidemiological Investigation of Helicobacter Pylori-infected Patients and the Effect of Eradication Treatment on Dyspepsia Symptoms
Led by Shanghai Jiao Tong University School of Medicine · Updated on 2024-12-30
2242
Participants Needed
26
Research Sites
N/A
Total Duration
On this page
AI-Summary
What this Trial Is About
Researchers are conducting a multicenter, prospective observational study to investigate how often patients with Helicobacter pylori infection experience dyspeptic symptoms, such as indigestion. The study also aims to follow these patients after they undergo treatment to eradicate H. pylori to see how their dyspeptic symptoms improve over time. This research intends to guide better diagnosis and treatment strategies for patients with H. pylori infection and related digestive discomfort. Participants diagnosed with H. pylori infection confirmed by breath tests or gastroscopy will complete an epidemiological questionnaire and a Functional Dyspepsia Symptom Diary (FDSD) to record their symptoms. Patients who have dyspepsia and successfully clear the infection will be followed up at 2 months and again at 6 months to assess if their symptoms have improved. The study does not involve any experimental drugs or treatments but focuses on observation and symptom tracking. During the study, patients will provide basic health information and record their digestive symptoms in the diary. Researchers will track the occurrence of dyspepsia at the start and monitor symptom relief after treatment. The follow-up periods at 2 and 6 months after eradication therapy will help measure symptom changes. Participants may be involved for several months, contributing to a better understanding of the natural history of H. pylori-related dyspepsia and treatment outcomes.
CONDITIONS
Brief Title
Epidemiological Investigation of Helicobacter Pylori-infected Patients and the Effect of Eradication Treatment on Dyspepsia Symptoms
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Male or female patients aged 18-80 years
- Diagnosed with Helicobacter pylori infection by 13C/14C breath test or gastroscopy
- Treatment-naive for Helicobacter pylori infection
- Able and willing to participate and provide informed consent
You will not qualify if you...
- Under 18 or over 80 years old
- Have organic digestive diseases such as active peptic ulcer, gastroesophageal reflux, gastrointestinal bleeding, pancreatitis, cholecystitis, gallstones, intestinal obstruction, or inflammatory bowel disease
- Have alarm symptoms like melena, vomiting blood, anemia, or unexplained weight loss
- Pregnant or breastfeeding women
- History of cancer
- History of subtotal gastrectomy
- Severe organ dysfunction or congenital diseases such as advanced heart failure, liver failure, uremia, respiratory failure, hemophilia, or Wilson's disease
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - 1 day
Participants undergo tests to confirm Helicobacter pylori infection and complete epidemiological questionnaires and symptom diaries to assess dyspepsia symptoms.
1 visit (in-person)
Duration - 6 months
Participants who have successfully eradicated Helicobacter pylori infection are followed up to monitor relief of dyspepsia symptoms.
2 follow-up visits at 2 months and 6 months (in-person)
Trial Site Locations
Total: 26 locations
1
Chongqing Daping Hospital
Chongqing, Chongqing Municipality, China
Actively Recruiting
2
The Ninth People's Hospital of Chongqing
Chongqing, Chongqing Municipality, China
Actively Recruiting
3
The People's Hospital of Kaizhou District, CQ
Chongqing, Chongqing Municipality, China
Actively Recruiting
4
The First Affiliated Hospital of Xiamen University
Xiamen, Fujian, China
Actively Recruiting
5
The People's Hospital of Wuwei
Wuwei, Gansu, China
Actively Recruiting
6
The First People's Hospital of Qinzhou
Qinzhou, Guangxi, China
Actively Recruiting
7
The First Affiliated Hospital of Henan University of Science and Technology
Luoyang, Henan, China
Actively Recruiting
8
Yongcheng People's Hospital of Henan Province
Shangqiu, Henan, China
Actively Recruiting
9
Xuchang Central Hospital
Xuchang, Henan, China
Actively Recruiting
10
Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
Wuhan, Hubei, China
Actively Recruiting
11
Baotou Central Hospital
Baotou, Inner Mongolia, China
Actively Recruiting
12
Dalian Friendship Hospital
Dalian, Liaoning, China
Actively Recruiting
13
The First Affiliated Hospital of Dalian Medical University
Dalian, Liaoning, China
Actively Recruiting
14
Renji Hospital, School of Medicine, Shanghai Jiao Tong University
Shanghai, Shanghai Municipality, China, 200127
Actively Recruiting
15
Ruijin Hospital Luwan Branch
Shanghai, Shanghai Municipality, China
Actively Recruiting
16
Shanghai Construction Group Hospital
Shanghai, Shanghai Municipality, China
Actively Recruiting
17
Shanghai East Hospital
Shanghai, Shanghai Municipality, China
Actively Recruiting
18
Shanghai Putuo Liqun Hospital
Shanghai, Shanghai Municipality, China
Actively Recruiting
19
Shanghai Songjiang Central Hospital
Shanghai, Shanghai Municipality, China
Actively Recruiting
20
West China Fourth Hospital, Sichuan University
Chengdu, Sichuan, China
Actively Recruiting
21
First Teaching Hospital of Tianjin University of Traditional Chinese Medicine
Tianjing, Tianjing, China
Actively Recruiting
22
The Second People's Hospital of Kashgar, Xinjiang
Kashgar, Xinjiang, China
Actively Recruiting
23
Second People's Hospital of Jinning District, Kunming City
Kunming, Yunnan, China
Actively Recruiting
24
Ningbo Hangzhou Bay Hospital
Ningbo, Zhejiang, China
Actively Recruiting
25
The People's Hospital of Shengzhou
Ningbo, Zhejiang, China
Actively Recruiting
26
Shengzhou People's Hospital
Shaoxing, Zhejiang, China
Actively Recruiting
Research Team
H
Hong Lu, MD
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
Similar Trials
Frequently Asked Questions
Have more questions? Get in touch with our team for quick support
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here