A Multi-Centre Epidemiology Study on Neonatal Seizure in China

What this Trial Is About

This research aims to describe how often new seizures start or are newly diagnosed in newborn babies up to 28 days old. It focuses on babies with uncontrolled seizures, which can be linked to high-risk factors during the time around birth. Researchers study abnormal electrical activity in the brain to understand these seizures better. To do this, the study uses electroencephalography (EEG) to monitor and record brain electrical activity in newborns suspected of having seizures. Along with EEG recordings, information about the babies' demographics, medical history, family background, birth details, growth, and feeding is collected through medical records and questionnaires. This helps identify factors that may influence seizure occurrence in newborns. Participants will be followed from birth until 28 days old to record seizure incidence and monitor brain activity using EEG within 14 days after any seizure. At 18 months corrected age, neurodevelopment and neurological function are assessed using specific scoring systems. Genetic testing is also done within 30 days of DNA sample collection. The study collects detailed information to better understand seizure risks and outcomes in newborns.

Epidemiology Study on Neonatal Seizure